Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A2 | O15244 | 2/20 | 0.46 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.46 |
| ▸ | HTR3B | O95264 | 2/20 | 0.46 |
| ▸ | HTR3A | P46098 | 2/20 | 0.46 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.46 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.46 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.46 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.46 |
| ▸ | PLAU | P00749 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.43 |
| ▸ | NOS1 | P29475 | 5/20 | 0.40 |
| ▸ | NOS3 | P29474 | 4/20 | 0.40 |
| ▸ | NOS2 | P35228 | 2/20 | 0.40 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17329388 | 0.88 | SLC22A2 (0.43) | SLC22A2HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL3921499 | 0.82 | SIGMAR1 (0.51) | SLC22A2HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL17360623 | 0.78 | SLC22A2 (0.50) | SLC22A2HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL3919033 | 0.78 | MEN1 (0.54) | SLC22A2HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL7562289 | 0.73 | SLC22A2 (0.44) | SLC22A2HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL109210 | 0.71 | HTR3E (0.54) | SLC22A2HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL6049836 | 0.71 | HTR3E (0.54) | SLC22A2HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL2478435 | 0.70 | HTR3E (0.52) | SLC22A2HTR3EHTR3BHTR3AHTR3D | |
| Bromide SCHEMBL31532276 | 0.70 | NOS1 (0.54) | SLC22A2HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL2478437 | 0.70 | HTR3E (0.52) | SLC22A2HTR3EHTR3BHTR3AHTR3D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2960284-B1 | RUBBER COMPOSITION, AND PNEUMATIC TIRE USING SAME | BRIDGESTONE CORP (JP) | 2018-08-01 | — | — | EP | claimed |
| US-20150361248-A1 | RUBBER COMPOSITION, AND PNEUMATIC TIRE USING SAME | OTSUKA CHEMICAL CO., LTD. (JP) | 2015-12-17 | — | — | US | claimed |
| US-10053553-B2 | Rubber composition, and pneumatic tire using same | BRIDGESTONE CORPORATION (JP) | 2018-08-21 | — | — | US | disclosed |
| EP-2960284-B1 | RUBBER COMPOSITION, AND PNEUMATIC TIRE USING SAME | BRIDGESTONE CORP (JP) | 2018-08-01 | — | — | EP | disclosed |
| US-9890267-B2 | Rubber composition for tires and pneumatic tire | BRIDGESTONE CORPORATION (JP) | 2018-02-13 | — | — | US | disclosed |
| EP-2977401-B1 | RUBBER COMPOSITION FOR TIRES AND PNEUMATIC TIRE | BRIDGESTONE CORP (JP) | 2017-06-14 | — | — | EP | disclosed |
| EP-2977401-A1 | RUBBER COMPOSITION FOR TIRES AND PNEUMATIC TIRE | Bridgestone Corporation (JP) | 2016-01-27 | — | — | EP | disclosed |
| US-20160017124-A1 | RUBBER COMPOSITION FOR TIRES AND PNEUMATIC TIRE | BRIDGESTONE CORPORATION (JP) | 2016-01-21 | — | — | US | disclosed |
| US-20150361248-A1 | RUBBER COMPOSITION, AND PNEUMATIC TIRE USING SAME | OTSUKA CHEMICAL CO., LTD. (JP) | 2015-12-17 | — | — | US | disclosed |