Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | AR | P10275 | 10/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.35 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.35 |
| ▸ | ERN1 | O75460 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1666428 | 0.84 | ALDH1A1 (0.42) | ALDH1A1LMNAARMAPTHTT | |
| SCHEMBL12766718 | 0.83 | AR (0.44) | ARERN1 | |
| SCHEMBL8618279 | 0.80 | LMNA (0.48) | ALDH1A1LMNAMAPTHTT | |
| SCHEMBL21661959 | 0.78 | AR (0.40) | ALDH1A1LMNAARMAPTHTT | |
| SCHEMBL9701681 | 0.78 | LMNA (0.46) | ALDH1A1LMNAMAPTHTT | |
| SCHEMBL9701635 | 0.78 | LMNA (0.50) | ALDH1A1LMNAMAPTHTT | |
| SCHEMBL1666562 | 0.75 | AR (0.37) | ALDH1A1LMNAARNPSR1RAB9A | |
| SCHEMBL12679971 | 0.75 | LMNA (0.50) | ALDH1A1LMNAARMAPTHTT | |
| SCHEMBL6294085 | 0.75 | LMNA (0.48) | ALDH1A1LMNAMAPTHTT | |
| SCHEMBL11755163 | 0.74 | MEN1 (0.39) | ALDH1A1LMNAARMAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2041123-A2 | FUSED CYCLIC COMPOUNDS | Takeda Pharmaceutical Company Limited (JP) | 2009-04-01 | — | — | EP | disclosed |
| WO-2008001931-A2 | FUSED CYCLIC COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-01-03 | — | — | WO | disclosed |