Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 7/20 | 0.40 |
| ▸ | NOS3 | P29474 | 5/20 | 0.40 |
| ▸ | NOS2 | P35228 | 5/20 | 0.40 |
| ▸ | DDB1 | Q16531 | 4/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 4/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | ANPEP | P15144 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9559207 | 0.77 | NOS1 (0.47) | NOS1NOS3NOS2ADRA1A | |
| SCHEMBL5518924 | 0.76 | NOS1 (0.41) | NOS1NOS3NOS2DDB1CRBN | |
| SCHEMBL30074503 | 0.75 | NOS1 (0.50) | NOS1NOS3NOS2ADRA1A | |
| SCHEMBL145755 | 0.75 | NOS1 (0.50) | NOS1NOS3NOS2ADRA1A | |
| SCHEMBL27199706 | 0.70 | NOS1 (0.38) | NOS1NOS3NOS2 | |
| SCHEMBL1012779 | 0.69 | NOS1 (0.40) | NOS1NOS3NOS2ADRA1A | |
| SCHEMBL16115899 | 0.69 | NOS1 (0.44) | NOS1NOS3NOS2 | |
| SCHEMBL29357835 | 0.69 | NOS1 (0.40) | NOS1NOS3NOS2ADRA1A | |
| SCHEMBL165957 | 0.69 | NOS1 (0.42) | NOS1NOS3NOS2ADRA1A | |
| SCHEMBL441521 | 0.68 | NOS1 (0.39) | NOS1NOS3NOS2DDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1828141-A4 | A ONE-POT PROCESS FOR THE PREPARATION OF ANTIEMETIC AGENT, 1,2,3,9-TETRAHYDRO-9-METHYL-3[(2-METHYL)-1H-IMIDAZOLE-1-YL)METHYL]-4H-CARBAZOL-4-O | IPCA LAB LTD (IN) | 2009-04-01 | — | — | EP | disclosed |
| EP-1828141-A1 | A ONE-POT PROCESS FOR THE PREPARATION OF ANTIEMETIC AGENT, 1,2,3,9-TETRAHYDRO-9-METHYL-3[(2-METHYL)-1H-IMIDAZOLE-1-YL)METHYL]-4H-CARBAZOL-4-O | IPCA Laboratories Limited (IN) | 2007-09-05 | — | — | EP | disclosed |
| WO-2006046253-A1 | A ONE-POT PROCESS FOR THE PREPARATION OF ANTIEMETIC AGENT, 1,2,3,9-TETRAHYDRO-9-METHYL-3[(2-METHYL)-1H-IMIDAZOLE-1-YL)METHYL]-4H-CARBAZOL-4-O | IPCA LABORATORIES LIMITED (IN) | 2006-05-04 | — | — | WO | disclosed |