Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 7/20 | 0.50 |
| ▸ | NOS2 | P35228 | 5/20 | 0.46 |
| ▸ | NOS3 | P29474 | 4/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL145755 | 1.00 | NOS1 (0.50) | NOS1NOS2NOS3ADRA1AADRA2A | |
| SCHEMBL9559207 | 0.94 | NOS1 (0.47) | NOS1NOS2NOS3ADRA1AADRA2A | |
| SCHEMBL3880710 | 0.76 | CYP19A1 (0.44) | NOS1ALDH1A1KDM4EACHE | |
| SCHEMBL1005903 | 0.76 | NOS1 (0.41) | NOS1NOS2NOS3ADRA1AADRA2A | |
| SCHEMBL3922142 | 0.75 | NOS1 (0.40) | NOS1NOS2NOS3ADRA1A | |
| SCHEMBL7502383 | 0.73 | ALDH1A1 (0.43) | ALDH1A1KDM4EMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL5474778 | 0.73 | NOS1 (0.39) | NOS1NOS2NOS3ADRA1A | |
| SCHEMBL28868450 | 0.72 | HCAR3 (0.38) | ALDH1A1KDM4EKMT2A | |
| SCHEMBL16115899 | 0.71 | NOS1 (0.44) | NOS1NOS2NOS3 | |
| SCHEMBL5518924 | 0.71 | NOS1 (0.41) | NOS1NOS2NOS3ADRA1AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113402446-B | 3-amino 4-hydroxycarbazole compound, preparation method and application | 台州学院 | 2023-01-10 | — | — | CN | disclosed |