Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.60 |
| ▸ | HPGD | P15428 | 4/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | NPC1 | O15118 | 3/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | CES2 | O00748 | 1/20 | 0.55 |
| ▸ | CES1 | P23141 | 1/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL561093 | 0.87 | ALDH1A1 (0.61) | PTPN1SMN1; SMN2HPGDKDM4EALDH1A1 | |
| SCHEMBL3221672 | 0.86 | SMN1; SMN2 (0.47) | PTPN1SMN1; SMN2HPGDKDM4EALDH1A1 | |
| SCHEMBL30623333 | 0.79 | SMN1; SMN2 (0.72) | PTPN1SMN1; SMN2HPGDKDM4EALDH1A1 | |
| SCHEMBL1317943 | 0.79 | SMN1; SMN2 (0.72) | PTPN1SMN1; SMN2HPGDKDM4EALDH1A1 | |
| SCHEMBL29489791 | 0.79 | PTPN1 (0.71) | PTPN1SMN1; SMN2HPGDKDM4EALDH1A1 | |
| SCHEMBL1974978 | 0.79 | PTPN1 (0.71) | PTPN1SMN1; SMN2HPGDKDM4EALDH1A1 | |
| SCHEMBL685950 | 0.78 | SMN1; SMN2 (0.52) | PTPN1SMN1; SMN2HPGDKDM4EALDH1A1 | |
| SCHEMBL30375368 | 0.77 | PTPN1 (0.69) | PTPN1SMN1; SMN2HPGDKDM4EALDH1A1 | |
| SCHEMBL1448153 | 0.77 | PTPN1 (0.69) | PTPN1SMN1; SMN2HPGDKDM4EALDH1A1 | |
| SCHEMBL28345275 | 0.77 | PTPN1 (0.69) | PTPN1SMN1; SMN2HPGDKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1791888-B1 | POLYCYCLOOLEFIN POLYMERIC COMPOSITIONS FOR SEMICONDUCTOR APPLICATIONS | PROMERUS LLC (US) | 2009-03-25 | — | — | EP | disclosed |
| EP-1791888-A1 | POLYCYCLOOLEFIN POLYMERIC COMPOSITIONS FOR SEMICONDUCTOR APPLICATIONS | Promerus, LLC (US) | 2007-06-06 | — | — | EP | disclosed |
| WO-2006023511-A1 | POLYCYCLOOLEFIN POLYMERIC COMPOSITIONS FOR SEMICONDUCTOR APPLICATIONS | PROMERUS LLC (US) | 2006-03-02 | — | — | WO | disclosed |
| US-20060041093-A1 | Polycycloolefin polymeric compositions for semiconductor applications | SUMITOMO BAKELITE CO., LTD. (JP) | 2006-02-23 | — | — | US | disclosed |