Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A5 | Q9Y345 | 8/20 | 0.75 |
| ▸ | SLC6A9 | P48067 | 12/20 | 0.73 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3925116 | 0.97 | SLC6A5 (0.79) | SLC6A5SLC6A9HPGDALDH1A1NPC1 | |
| Ammonia Solution, Strong SCHEMBL3929225 | 0.96 | SLC6A5 (0.78) | SLC6A5SLC6A9HPGDALDH1A1NPC1 | |
| Methylamine SCHEMBL3923289 | 0.95 | SLC6A5 (0.76) | SLC6A5SLC6A9HPGDALDH1A1NPC1 | |
| SCHEMBL3929509 | 0.93 | SLC6A5 (0.86) | SLC6A5SLC6A9HPGDALDH1A1NPC1 | |
| SCHEMBL3917876 | 0.90 | SLC6A5 (0.75) | SLC6A5SLC6A9HPGDALDH1A1NPC1 | |
| SCHEMBL3927647 | 0.88 | SLC6A5 (0.78) | SLC6A5SLC6A9HPGDALDH1A1NPC1 | |
| SCHEMBL3923294 | 0.87 | SLC6A5 (0.71) | SLC6A5SLC6A9HPGDALDH1A1NPC1 | |
| SCHEMBL3928542 | 0.86 | SLC6A5 (0.75) | SLC6A5SLC6A9HPGDALDH1A1NPC1 | |
| SCHEMBL3931232 | 0.86 | SLC6A5 (1.00) | SLC6A5SLC6A9HPGDALDH1A1NPC1 | |
| SCHEMBL3928898 | 0.86 | SLC6A5 (0.78) | SLC6A5SLC6A9HPGDALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7595314-B2 | Benzoyl-piperazine derivatives | HOFFMANN-LA ROCHE INC. (US) | 2009-09-29 | — | — | US | disclosed |
| US-20090192136-A1 | BENZOYL-PIPERAZINE DERIVATIVES | ALBERATI-GIANI DANIELA | 2009-07-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090192136-A1 | BENZOYL-PIPERAZINE DERIVATIVES | OPRL1, ACHE, PNMT | SLC6A5 2174/4885SLC6A9 4305/4885HPGD 1651/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.