Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | MPI | P34949 | 1/20 | 0.53 |
| ▸ | GPR84 | Q9NQS5 | 9/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.45 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | NQO1 | P15559 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29805130 | 1.00 | MEN1 (0.53) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL31655459 | 0.95 | MEN1 (0.47) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| Phosphonic Acid SCHEMBL30415639 | 0.93 | GPR84 (0.47) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| Phosphonic Acid SCHEMBL30414887 | 0.92 | GPR84 (0.49) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL3916569 | 0.89 | ESR1 (0.49) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL14327785 | 0.89 | GPR84 (0.50) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL29510114 | 0.86 | MEN1 (0.58) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL30275493 | 0.86 | MEN1 (0.58) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL3262604 | 0.86 | MEN1 (0.58) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL2528988 | 0.85 | MEN1 (0.54) | MEN1KMT2AKDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108658774-B | Synthesis method of novel chiral nitrobinaphthol and derivatives thereof | 中国科学院青岛生物能源与过程研究所 | 2020-11-27 | — | — | CN | claimed |
| CN-108658774-B | Synthesis method of novel chiral nitrobinaphthol and derivatives thereof | 中国科学院青岛生物能源与过程研究所 | 2020-11-27 | — | — | CN | disclosed |
| CN-108658774-A | A kind of synthetic method of novel chiral nitro dinaphthol and its derivative | 中国科学院青岛生物能源与过程研究所 | 2018-10-16 | — | — | CN | disclosed |
| US-7517828-B2 | Chiral broensted acid catalyst for asymmetric synthesis and method of asymmetric synthesis with the catalyst | TOAGOSEI CO., LTD. (JP) | 2009-04-14 | — | — | US | disclosed |
| US-20060276329-A1 | Asymmetric synthesis catalyst based on chiral brsnsted acid and method of asymmetric synthesis with the catalyst | TOAGOSEI CO., LTD. (JP) | 2006-12-07 | — | — | US | disclosed |
| US-6855657-B2 | Ortho substituted chiral phosphines and phosphinites and their use in asymmetric catalytic reactions | THE PENN STATE RESEARCH FOUNDATION (US) | 2005-02-15 | — | — | US | disclosed |
| US-20040068126-A1 | Ortho substituted chiral phosphines and phosphinites and their use in asymmetric catalytic reactions | THE PENN STATE RESEARCH FOUNDATION | 2004-04-08 | — | — | US | disclosed |
| US-6653485-B2 | Particularly effective in Ru-catalyzed asymmetric hydrogenation of beta-ketoesters to beta-hydroxyesters and ruthenium-catalyzed asymmetric hydrogenation of enamides to beta amino acids; catalyst selectivity | THE PENN STATE RESEARCH FOUNDATION | 2003-11-25 | — | — | US | disclosed |
| US-20020128501-A1 | Particularly effective in Ru-catalyzed asymmetric hydrogenation of beta-ketoesters to beta-hydroxyesters and ruthenium-catalyzed asymmetric hydrogenation of enamides to beta amino acids; catalyst selectivity | THE PENN STATE RESEARCH FOUNDATION | 2002-09-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040068126-A1 | Ortho substituted chiral phosphines and phosphinites and their use in asymmetric catalytic reactions | BCKDK, PDK3, HCK | MEN1 1900/4885KMT2A 975/4885KDM4E 2838/4885 |
| US-20020128501-A1 | Particularly effective in Ru-catalyzed asymmetric hydrogenation of beta-ketoesters to beta-hydroxyesters and ruthenium-catalyzed asymmetric hydrogenation of enamides to beta amino acids; catalyst selectivity | HRH4, BCKDK, HRH3 | MEN1 2086/4885KMT2A 1234/4885KDM4E 2902/4885 |
| US-20060276329-A1 | Asymmetric synthesis catalyst based on chiral brsnsted acid and method of asymmetric synthesis with the catalyst | LSS, COASY, FASN | MEN1 169/4885KMT2A 2039/4885KDM4E 4508/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.