Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | MGAM | O43451 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 3/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 7/20 | 0.35 |
| ▸ | NNMT | P40261 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15516376 | 0.86 | PIM1 (0.41) | PIM1MGAMALDH1A1GAAMAPT | |
| SCHEMBL6231133 | 0.82 | MGAM (0.38) | MGAMALDH1A1GAAMAPTCNR2 | |
| SCHEMBL5873635 | 0.81 | ALDH1A1 (0.61) | ALDH1A1GAAMAPTHDAC8KDM4E | |
| SCHEMBL530121 | 0.78 | KMT2A (0.37) | MGAMALDH1A1GAAMAPTCNR2 | |
| SCHEMBL28347669 | 0.78 | MAPK1 (0.40) | ALDH1A1GAAMAPTCNR2HDAC8 | |
| SCHEMBL5801074 | 0.75 | CYP1A2 (0.39) | ALDH1A1LMNANFKB1RAB9ANFKB2 | |
| SCHEMBL29540332 | 0.73 | MGAM (0.68) | PIM1MGAMALDH1A1GAAMAPT | |
| SCHEMBL367913 | 0.73 | MGAM (0.68) | PIM1MGAMALDH1A1GAAMAPT | |
| SCHEMBL5788456 | 0.72 | MGAM (0.66) | PIM1MGAMALDH1A1GAAMAPT | |
| Hydrochloric Acid SCHEMBL3400880 | 0.72 | MGAM (0.66) | PIM1MGAMALDH1A1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009007396-A1 | NONSTEROIDAL PROGESTERONE RECEPTOR MODULATORS | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-01-15 | — | — | WO | disclosed |