Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.41 |
| ▸ | NOS3 | P29474 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 1/20 | 0.41 |
| ▸ | NOS2 | P35228 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1467047 | 0.76 | SLC6A2 (0.52) | IDO1NOS3NOS1NOS2POLB | |
| SCHEMBL10899765 | 0.75 | L3MBTL1 (0.47) | POLBPPARGPPARACYP1A2CYP3A4 | |
| SCHEMBL560907 | 0.75 | PPARG (0.45) | POLBPPARGPPARACYP1A2CYP3A4 | |
| SCHEMBL11234251 | 0.75 | IDO1 (0.41) | IDO1NOS3NOS1NOS2POLB | |
| SCHEMBL10976269 | 0.75 | IDO1 (0.41) | IDO1NOS3NOS1NOS2POLB | |
| Hydrochloric Acid SCHEMBL1466263 | 0.75 | SLC6A2 (0.50) | IDO1NOS3NOS1NOS2POLB | |
| SCHEMBL6461635 | 0.73 | EPHX1 (0.54) | IDO1NOS3NOS1NOS2POLB | |
| SCHEMBL23998029 | 0.71 | TP53 (0.44) | IDO1NOS3NOS1NOS2POLB | |
| SCHEMBL7215558 | 0.71 | PPARG (0.42) | POLBCTSLCTSBCA12CA1 | |
| SCHEMBL4850434 | 0.71 | PPARG (0.42) | POLBHSD17B10PPARGPPARACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118598777-A | Preparation method of difluoromethane sulfonyl chloride | 衢州市九洲化工有限公司 | 2024-09-06 | — | — | CN | claimed |
| CN-116063208-A | Synthesis method of difluoromethane sulfonyl chloride | 安徽省化工研究院 | 2023-05-05 | — | — | CN | claimed |
| CN-118598777-A | Preparation method of difluoromethane sulfonyl chloride | 衢州市九洲化工有限公司 | 2024-09-06 | — | — | CN | disclosed |
| CN-118598777-A | Preparation method of difluoromethane sulfonyl chloride | 衢州市九洲化工有限公司 | 2024-09-06 | — | — | CN | disclosed |
| CN-117049996-A | Synthesis method of 3-difluoromethylthio substituted indole compound | 都创(上海)医药科技股份有限公司 | 2023-11-14 | — | — | CN | disclosed |
| CN-116063208-A | Synthesis method of difluoromethane sulfonyl chloride | 安徽省化工研究院 | 2023-05-05 | — | — | CN | disclosed |
| CN-116063208-A | Synthesis method of difluoromethane sulfonyl chloride | 安徽省化工研究院 | 2023-05-05 | — | — | CN | disclosed |
| CN-107540598-B | Method for preparing N-difluoromethylthio phthalimide compound | 中国科学院上海有机化学研究所 | 2020-05-12 | — | — | CN | disclosed |
| CN-107540598-A | A kind of method for preparing N difluoro methyl mercapto neighbour's benzoylimino class compounds | 中国科学院上海有机化学研究所 | 2018-01-05 | — | — | CN | disclosed |
| CN-100509776-C | Method for synthesis of hydrogenofluoromethylenesulphonyl radical derivatives | RHONE POULENC CHIMIE (FR) | 2009-07-08 | — | — | CN | disclosed |
| US-7534906-B2 | Process for the synthesis of hydrogenofluoromethylenesulphonyl radical derivatives | RHODIA CHIMIE (FR) | 2009-05-19 | — | — | US | disclosed |
| CN-1671657-A | Method for synthesis of hydrogenofluoromethylenesulphonyl radical derivatives | RHONE POULENC CHIMIE (FR) | 2005-09-21 | — | — | CN | disclosed |
| JP-2005112810-A | METHOD FOR PRODUCING BENZYL(DIFLUOROMETHYL) SULFIDE COMPOUND | IHARA CHEM IND CO LTD | 2005-04-28 | — | — | JP | disclosed |
| JP-2003128644-A | METHOD FOR PRODUCING BENZYL(DIFLUOROMETHYL)SULFIDE | NIPPON NOHYAKU CO LTD | 2003-05-08 | — | — | JP | disclosed |
| WO-2002066423-A1 | PROCESS FOR PREPARATION OF POLYFLUOROALKYLSULFENYL COMPOUNDS | NIHON NOHYAKU CO., LTD. (JP) | 2002-08-29 | — | — | WO | disclosed |
| US-4529721-A | Human and veterinary bactericide | SHIONOGI & CO., LTD. (JP) | 1985-07-16 | — | — | US | disclosed |
| EP-0107928-A1 | Vinylthioacetamido oxacephalosporin derivatives, and intermediates therefor, their preparation, formulations containing the same and their antibacterial use | SHIONOGI & CO., LTD. (JP) | 1984-05-09 | — | — | EP | disclosed |
| EP-0008854-A1 | Pentadienone hydrazone, and its use as insecticidal agent | AMERICAN CYANAMID COMPANY (US) | 1980-03-19 | — | — | EP | disclosed |
| US-4191768-A | Pentadienone hydrazones, method for preparing the same, and insecticidal use thereof | AMERICAN CYANAMID COMPANY (US) | 1980-03-04 | — | — | US | disclosed |
| US-3932508-A | Polyfluoromethylthio-substituted compounds | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1976-01-13 | — | — | US | disclosed |