Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 14/20 | 0.54 |
| ▸ | IDO1 | P14902 | 3/20 | 0.46 |
| ▸ | NOS3 | P29474 | 1/20 | 0.46 |
| ▸ | NOS1 | P29475 | 1/20 | 0.46 |
| ▸ | NOS2 | P35228 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7080143 | 0.81 | EPHX1 (0.53) | EPHX1IDO1NOS3NOS1NOS2 | |
| SCHEMBL27633675 | 0.81 | EPHX1 (0.59) | EPHX1IDO1NOS3NOS1NOS2 | |
| SCHEMBL7106175 | 0.78 | EPHX1 (0.50) | EPHX1IDO1NOS3NOS1NOS2 | |
| SCHEMBL7873176 | 0.78 | EPHX1 (0.70) | EPHX1POLB | |
| SCHEMBL7396452 | 0.78 | EPHX1 (0.70) | EPHX1POLB | |
| SCHEMBL11204748 | 0.75 | EPHX1 (0.55) | EPHX1IDO1NOS3NOS1NOS2 | |
| SCHEMBL6807037 | 0.74 | EPHX1 (0.47) | EPHX1IDO1NOS3NOS1NOS2 | |
| SCHEMBL3922984 | 0.73 | IDO1 (0.41) | EPHX1IDO1NOS3NOS1NOS2 | |
| SCHEMBL6954426 | 0.72 | PPARG (0.49) | EPHX1IDO1POLBCYP2C19 | |
| SCHEMBL9854865 | 0.71 | ALDH1A1 (0.49) | EPHX1IDO1NOS3NOS1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1608643-A1 | 6-SULFONAMIDE QUINOLINE AND CHROMENE DERIVATIVE AS ANDROGEN RECEPTOR ANTAGONISTS | Warner-Lambert Company LLC (US) | 2005-12-28 | — | — | EP | disclosed |
| WO-2004083204-A1 | 6-SULFONAMIDE QUINOLINE AND CHROMENE DERIVATIVE AS ANDROGEN RECEPTOR ANTAGONISTS | WARNER-LAMBERT COMPANY LLC (US) | 2004-09-30 | — | — | WO | disclosed |