Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 4/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19357539 | 1.00 | FFAR3 (0.37) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL8600596 | 0.91 | HDAC3 (0.40) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL7545293 | 0.88 | CES1 (0.39) | ALDH1A1CES2CES1TSHR | |
| SCHEMBL188481 | 0.87 | FFAR3 (0.36) | FFAR3ALDH1A1TSHR | |
| SCHEMBL8673175 | 0.86 | AKR1B1 (0.43) | ALDH1A1CES2CES1TSHR | |
| SCHEMBL8673179 | 0.86 | AKR1B1 (0.43) | ALDH1A1CES2CES1TSHR | |
| SCHEMBL540776 | 0.85 | GPR84 (0.45) | ALDH1A1CES2CES1TSHR | |
| SCHEMBL7552128 | 0.84 | CES1 (0.39) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL23204219 | 0.82 | MAPK10 (0.39) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL23163159 | 0.82 | MAPK10 (0.39) | FFAR3HDAC3HDAC1HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017158151-A1 | PYRIMIDONE DERIVATIVES AND THEIR USE IN THE TREATMENT, AMELIORATION OR PREVENTION OF A VIRAL DISEASE | SAVIRA PHARMACEUTICALS GMBH (AT) | 2017-09-21 | — | — | WO | disclosed |
| EP-1807457-A4 | VINYL CHLORIDE RESIN COMPOSITION AND METHOD FOR PREPARATION THEREOF | LG CHEMICAL LTD (KR) | 2009-03-25 | — | — | EP | disclosed |
| EP-1807457-A1 | VINYL CHLORIDE RESIN COMPOSITION AND METHOD FOR PREPARATION THEREOF | LG Chem, Ltd. (KR) | 2007-07-18 | — | — | EP | disclosed |
| WO-2006049392-A1 | VINYL CHLORIDE RESIN COMPOSITION AND METHOD FOR PREPARATION THEREOF | LG CHEM, LTD. (KR) | 2006-05-11 | — | — | WO | disclosed |
| US-5843951-A | Analgesic composition of pyrazolo(1,5-A) pyrimidines | OTSUKA PHARMACEUTICAL FACTORY INC. (JP) | 1998-12-01 | — | — | US | disclosed |
| EP-0795555-A1 | ANALGESICS | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1997-09-17 | — | — | EP | disclosed |