⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL81243 | 0.97 | MEN1 (0.39) | — | |
| SCHEMBL27854795 | 0.97 | MEN1 (0.39) | — | |
| Hydrochloric Acid SCHEMBL27404843 | 0.95 | MEN1 (0.37) | — | |
| SCHEMBL636365 | 0.88 | TSHR (0.37) | — | |
| SCHEMBL3923601 | 0.88 | — | — | |
| SCHEMBL22711078 | 0.84 | OPRM1 (0.34) | — | |
| SCHEMBL11543878 | 0.80 | OPRD1 (0.38) | — | |
| SCHEMBL18727479 | 0.80 | ALDH1A1 (0.42) | — | |
| SCHEMBL8767704 | 0.79 | KDM4E (0.35) | — | |
| SCHEMBL3248168 | 0.79 | SLC6A3 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118059905-A | Method for preparing methanol by integrating carbon dioxide trapping and hydrogenation by using Cu-based catalyst | 上海陕煤高新技术研究院有限公司 | 2024-05-24 | — | — | CN | claimed |
| CN-106946718-A | A kind of method for synthesizing efavirenz intermediate | 武汉工程大学 | 2017-07-14 | — | — | CN | claimed |
| WO-2002040073-A1 | ENDOSSEOUS IMPLANT | UNIVERSITÉ DE GENÈVE (CH) | 2002-05-23 | — | — | WO | claimed |
| CN-118184614-A | Substituted benzo five-membered unsaturated heterocyclic compounds, and preparation method and application thereof | 中国医学科学院医药生物技术研究所 | 2024-06-14 | — | — | CN | disclosed |
| CN-116535389-B | 6-Pyridine-3-quinoxaline urea derivative and application thereof | 四川大学 | 2024-05-03 | — | — | CN | disclosed |
| CN-116535389-A | 6-pyridine-3-quinoxaline urea derivative and application thereof | 四川大学 | 2023-08-04 | — | — | CN | disclosed |
| EP-3848363-B1 | TRICYCLIC SUBSTITUTED PIPERIDINE DIONE COMPOUND | MEDSHINE DISCOVERY INC (CN) | 2023-07-19 | — | — | EP | disclosed |
| CN-112689627-B | Tricyclic substituted piperidinediones | 南京明德新药研发有限公司 | 2022-03-29 | — | — | CN | disclosed |
| US-20210317109-A1 | TRICYCLIC SUBSTITUTED PIPERIDINE DIONE COMPOUND | MEDSHINE DISCOVERY INC. (CN) | 2021-10-14 | — | — | US | disclosed |
| EP-3856719-A1 | COMPOUNDS AS NEURONAL HISTAMINE RECEPTOR-3 ANTAGONISTS AND USES THEREOF | XWPharma Ltd. (KY) | 2021-08-04 | — | — | EP | disclosed |
| EP-3848363-A1 | TRICYCLIC SUBSTITUTED PIPERIDINE DIONE COMPOUND | Medshine Discovery Inc. (CN) | 2021-07-14 | — | — | EP | disclosed |
| EP-0400435-B1 | Carbonic half-ester of betaine structure | BASF AG (DE) | 1994-04-13 | — | — | EP | disclosed |
| EP-0177122-B1 | ACRYLAMIDE DERIVATIVES | Nippon Paint Co., Ltd. (JP) | 1992-04-01 | — | — | EP | disclosed |
| EP-0400435-A2 | Carbonic half-ester of betaine structure | BASF Aktiengesellschaft (DE) | 1990-12-05 | — | — | EP | disclosed |
| EP-0378930-A1 | Cyclic urea derivative | NIPPON PAINT CO., LTD. (JP) | 1990-07-25 | — | — | EP | disclosed |
| US-4935413-A | ELASTICITY, ADHESION AND DISPERSIBILITY | NIPPON PAINT CO., LTD. (JP) | 1990-06-19 | — | — | US | disclosed |
| US-4902727-A | Compounds having a polymerizable acylurethane structure, and their production and process of using | NIPPON PAINT CO., LTD. (JP) | 1990-02-20 | — | — | US | disclosed |
| EP-0236140-A2 | Carbostyril derivatives and salts thereof and anti-arrhythmic agents containing the carbostyril derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1987-09-09 | — | — | EP | disclosed |
| EP-0204497-A1 | Polymerisation process employing compounds having polymerisable acylurethane structures | Nippon Paint Co., Ltd. (JP) | 1986-12-10 | — | — | EP | disclosed |
| EP-0177122-A2 | Acrylamide derivatives | Nippon Paint Co., Ltd. (JP) | 1986-04-09 | — | — | EP | disclosed |