Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.34 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.32 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CACNA2D1 | P54289 | 6/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3928961 | 0.83 | SIGMAR1 (0.33) | SIGMAR1PLA2G1BPLA2G2ALMNACACNA2D1 | |
| SCHEMBL557630 | 0.79 | SIGMAR1 (0.41) | SIGMAR1PLA2G1BPLA2G2ALMNACACNA2D1 | |
| SCHEMBL2845490 | 0.78 | SIGMAR1 (0.35) | SIGMAR1LMNACACNA2D1 | |
| SCHEMBL18207967 | 0.77 | SIGMAR1 (0.35) | SIGMAR1PLA2G1BPLA2G2A | |
| SCHEMBL3922986 | 0.77 | SIGMAR1 (0.35) | SIGMAR1PLA2G1BPLA2G2ALMNA | |
| SCHEMBL16752022 | 0.77 | TSHR (0.35) | — | |
| SCHEMBL3921738 | 0.77 | SIGMAR1 (0.35) | SIGMAR1PLA2G1BPLA2G2ALMNA | |
| SCHEMBL2846589 | 0.77 | SIGMAR1 (0.34) | SIGMAR1LMNACACNA2D1 | |
| SCHEMBL2845488 | 0.76 | LMNA (0.36) | SIGMAR1LMNACACNA2D1 | |
| SCHEMBL14356493 | 0.76 | SPHK1 (0.45) | PLA2G1BPLA2G2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7572837-B2 | Process for the production of flexible polyurethane foams | TOSOH CORPORATION (JP) | 2009-08-11 | — | — | US | disclosed |
| US-20030144371-A1 | Catalyzing the copolymerization in presence of imidazole compounds, free of tin comound, forming polyetherurethane copolymers | TOSOH CORPORATION (JP) | 2003-07-31 | — | — | US | disclosed |
| EP-1312630-A1 | Process for the production of flexible polyurethane foams | Tosoh Corporation (JP) | 2003-05-21 | — | — | EP | disclosed |