SCHEMBL3923923

SCHEMBL3923923

CCCc1c(C)coc1C

nearest known ligand 0.39

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.39
ALDH1A2 O94788 2/20 0.39
ALDH2 P05091 2/20 0.39
ALDH1B1 P30837 2/20 0.39
ALDH1A3 P47895 2/20 0.39
NOS2 P35228 1/20 0.35
KDM4E B2RXH2 3/20 0.33
HPGD P15428 2/20 0.33
HSD17B10 Q99714 2/20 0.33
TSHR P16473 2/20 0.33
POLB P06746 1/20 0.33
LDHA P00338 1/20 0.30
LDHB P07195 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3929292 0.88 NPC1 (0.38) ALDH1A1ALDH1A2ALDH2ALDH1B1ALDH1A3
SCHEMBL4307196 0.80
SCHEMBL3929297 0.77 ALDH1A1 (0.37) ALDH1A1ALDH1A2ALDH2ALDH1B1ALDH1A3
SCHEMBL4307272 0.73
SCHEMBL14389407 0.73 ALDH1A1 (0.34) ALDH1A1ALDH1A2ALDH2ALDH1B1ALDH1A3
SCHEMBL4125542 0.70 ALDH1A2 (0.33) ALDH1A1ALDH1A2ALDH2ALDH1B1ALDH1A3
Formic Acid SCHEMBL28733547 0.70 ALDH1A1 (0.30) ALDH1A1
SCHEMBL20129902 0.70
SCHEMBL4134871 0.68 KDM4E (0.33) KDM4EPOLB
SCHEMBL3930085 0.67 MAPT (0.36) ALDH1A1ALDH1A2ALDH2ALDH1B1ALDH1A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7582712-B1 Alpha-olefins polymerization catalyst FORMOSA PLASTICS CORPORATION, U.S.A. (US) 2009-09-01 US claimed
US-7582712-B1 Alpha-olefins polymerization catalyst FORMOSA PLASTICS CORPORATION, U.S.A. (US) 2009-09-01 US disclosed
EP-2027101-A1 TRISUBSTITUTED FURAN DERIVATIVES AS FRAGRANCES AND AROMA SUBSTANCES Symrise GmbH & Co. KG (DE) 2009-02-25 EP disclosed
WO-2007131834-A1 TRISUBSTITUTED FURAN DERIVATIVES AS FRAGRANCES AND AROMA SUBSTANCES SYMRISE GMBH & CO. KG (DE) 2007-11-22 WO disclosed