SCHEMBL4134871

SCHEMBL4134871

C=CCc1c(C)coc1C

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.33
GLA P06280 1/20 0.33
GAA P10253 1/20 0.33
POLB P06746 1/20 0.32
NPSR1 Q6W5P4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4122376 0.74 KDM4E (0.33) KDM4EGLAGAA
SCHEMBL4125542 0.71 ALDH1A2 (0.33)
SCHEMBL4307272 0.70
SCHEMBL4133031 0.70
SCHEMBL4130120 0.70 MAPT (0.32) NPSR1
SCHEMBL4130757 0.70 MEN1 (0.32) POLB
SCHEMBL4132560 0.70
Formic Acid SCHEMBL28733547 0.67 ALDH1A1 (0.30)
SCHEMBL20129902 0.67
SCHEMBL3929292 0.67 NPC1 (0.38) KDM4ENPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2027101-A1 TRISUBSTITUTED FURAN DERIVATIVES AS FRAGRANCES AND AROMA SUBSTANCES Symrise GmbH & Co. KG (DE) 2009-02-25 EP claimed
WO-2007131834-A1 TRISUBSTITUTED FURAN DERIVATIVES AS FRAGRANCES AND AROMA SUBSTANCES SYMRISE GMBH & CO. KG (DE) 2007-11-22 WO claimed
JP-55066574-A None JP disclosed
EP-2027101-A1 TRISUBSTITUTED FURAN DERIVATIVES AS FRAGRANCES AND AROMA SUBSTANCES Symrise GmbH & Co. KG (DE) 2009-02-25 EP disclosed
WO-2007131834-A1 TRISUBSTITUTED FURAN DERIVATIVES AS FRAGRANCES AND AROMA SUBSTANCES SYMRISE GMBH & CO. KG (DE) 2007-11-22 WO disclosed
EP-0010761-B1 PROCESS FOR PREPARING 4-HYDROXY-2-CYCLOPENTEN-I-ONES, 2-METHYL-2,5-DIMETHOXY-2,5-DIHYDROFURANS AND A PROCESS FOR THEIR PREPARATION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1982-10-13 EP disclosed
US-4282372-A Process for producing cyclopentenolones SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1981-08-04 US disclosed
JP-S5566574-A NOVEL FURAN COMPOUND AND ITS PRODUCTION SUMITOMO CHEM CO LTD 1980-05-20 JP disclosed
EP-0010761-A1 Process for preparing 4-hydroxy-2-cyclopenten-I-ones, 2-methyl-2,5-dimethoxy-2,5-dihydrofurans and a process for their preparation SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1980-05-14 EP disclosed