Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28369306 | 0.94 | EPHX1 (0.33) | CYP2D6SCN9A | |
| SCHEMBL28369307 | 0.89 | NR1I2 (0.33) | CYP2D6SCN9A | |
| SCHEMBL11712734 | 0.82 | EPHX1 (0.43) | CYP2D6ALDH1A1NPSR1TSHRL3MBTL1 | |
| SCHEMBL28329179 | 0.82 | EPHX1 (0.40) | CYP2D6ALDH1A1NPSR1TSHRL3MBTL1 | |
| SCHEMBL6337110 | 0.81 | ALDH1A1 (0.38) | ALDH1A1SCN9A | |
| SCHEMBL10963755 | 0.81 | EPHX1 (0.46) | CYP2D6ALDH1A1NPSR1TSHRL3MBTL1 | |
| SCHEMBL28967437 | 0.81 | EPHX1 (0.46) | CYP2D6ALDH1A1NPSR1TSHRL3MBTL1 | |
| SCHEMBL10981025 | 0.80 | L3MBTL1 (0.39) | MEN1KMT2ACYP2D6ALDH1A1L3MBTL1 | |
| SCHEMBL6325837 | 0.80 | PTPN2 (0.35) | ALDH1A1SCN9A | |
| SCHEMBL6327829 | 0.77 | MGAM (0.44) | KMT2ACYP2D6ALDH1A1SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6774260-B2 | ALKYL 1-(3,3-DIMETHYLCYCLOHEXYL) ETHYL MALONATE DERIVATIVES; SOAPS, COSMETICS, PERFUMES, CLEANING COMPOUNDS, DETERGENTS; MUSKY ODOR | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2004-08-10 | — | — | US | claimed |
| US-20040053811-A1 | Fruity musk compositions | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2004-03-18 | — | — | US | claimed |
| EP-1398366-A1 | Fruity musk compositions | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2004-03-17 | — | — | EP | claimed |
| EP-2032516-A1 | FRAGRANCE COMPOUNDS | Givaudan SA (CH) | 2009-03-11 | — | — | EP | disclosed |
| WO-2007143873-A1 | FRAGRANCE COMPOUNDS | GIVAUDAN SA (CH) | 2007-12-21 | — | — | WO | disclosed |
| US-6919477-B2 | Fruity musk compositions | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2005-07-19 | — | — | US | disclosed |
| US-20040214745-A1 | Fruity musk compositions | BLEDSOE JAMES O (US) | 2004-10-28 | — | — | US | disclosed |
| US-20040209796-A1 | Fruity musk compositions | BLEDSOE JAMES O | 2004-10-21 | — | — | US | disclosed |
| US-6774260-B2 | ALKYL 1-(3,3-DIMETHYLCYCLOHEXYL) ETHYL MALONATE DERIVATIVES; SOAPS, COSMETICS, PERFUMES, CLEANING COMPOUNDS, DETERGENTS; MUSKY ODOR | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2004-08-10 | — | — | US | disclosed |
| US-20040053811-A1 | Fruity musk compositions | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2004-03-18 | — | — | US | disclosed |
| EP-1398366-A1 | Fruity musk compositions | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2004-03-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040209796-A1 | Fruity musk compositions | CUTA, DEK, MARCKS | MEN1 1751/4885KMT2A 2499/4885CYP2D6 2297/4885 |
| US-20040214745-A1 | Fruity musk compositions | CUTA, DEK, MARCKS | MEN1 1751/4885KMT2A 2499/4885CYP2D6 2297/4885 |
| US-20040053811-A1 | Fruity musk compositions | CUTA, DEK, MARCKS | MEN1 1751/4885KMT2A 2499/4885CYP2D6 2297/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.