Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | NUDT1 | P36639 | 4/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.31 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.31 |
| ▸ | PRKDC | P78527 | 1/20 | 0.31 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.30 |
| ▸ | OXTR | P30559 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7227702 | 0.85 | IDO1 (0.42) | CNR2TLR8ATMALDH1A1MAPT | |
| SCHEMBL5260014 | 0.74 | CYP1A2 (0.45) | ATMALDH1A1MAPTPRKDC | |
| SCHEMBL9362141 | 0.71 | ALDH1A1 (0.38) | TRPA1ALDH1A1MAPT | |
| SCHEMBL17626132 | 0.71 | MAPT (0.43) | TLR8ATMALDH1A1MAPT | |
| SCHEMBL3858714 | 0.71 | HTR2C (0.40) | TLR8HTR2CALDH1A1MAPT | |
| SCHEMBL467854 | 0.71 | IDO1 (0.45) | CNR2NUDT1HTR2C | |
| SCHEMBL17626050 | 0.71 | ENPP1 (0.38) | ALDH1A1MAPT | |
| SCHEMBL17626197 | 0.71 | PTPRC (0.43) | ALDH1A1MAPT | |
| SCHEMBL7325044 | 0.70 | ALDH1A2 (0.35) | ALDH1A1MAPT | |
| SCHEMBL2201317 | 0.70 | IDO1 (0.43) | CNR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2041102-A2 | HUMAN PROTEIN TYROSINE PHOSPHATASE INHIBITORS AND METHODS OF USE | The Procter & Gamble Company (US) | 2009-04-01 | — | — | EP | disclosed |
| WO-2008002569-A2 | HUMAN PROTEIN TYROSINE PHOSPHATASE INHIBITORS AND METHODS OF USE | THE PROCTER & GAMBLE COMPANY (US) | 2008-01-03 | — | — | WO | disclosed |