Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.42 |
| ▸ | GAA | P10253 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.41 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.41 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | HTT | P42858 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | S100B | P04271 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17659019 | 1.00 | KMT2A (0.42) | KMT2AGAAMEN1NPC1NR1I2 | |
| SCHEMBL17659703 | 0.98 | MEN1 (0.40) | KMT2AGAAMEN1NPC1NR1I2 | |
| Piperazine SCHEMBL28186647 | 0.91 | HTR5A (0.45) | KMT2AGAAMEN1NPC1NR1I2 | |
| SCHEMBL17659681 | 0.89 | GAA (0.41) | KMT2AGAAMEN1NPC1NR1I2 | |
| SCHEMBL29236372 | 0.89 | GAA (0.41) | KMT2AGAAMEN1NPC1NR1I2 | |
| SCHEMBL11441903 | 0.83 | ALDH1A1 (0.46) | KMT2AGAAMEN1NPC1ALDH1A1 | |
| SCHEMBL19381288 | 0.82 | ALDH1A1 (0.61) | KMT2AGAAMEN1NPC1ALDH1A1 | |
| SCHEMBL19381117 | 0.82 | ALDH1A1 (0.61) | KMT2AGAAMEN1NPC1ALDH1A1 | |
| SCHEMBL19381146 | 0.82 | ALDH1A1 (0.61) | KMT2AGAAMEN1NPC1ALDH1A1 | |
| SCHEMBL19381290 | 0.82 | ALDH1A1 (0.61) | KMT2AGAAMEN1NPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5714441-A | SYNTHETIC POLYOL ESTER BASED STOCK, TRIAZINE DERIVATIVE, SULFUR-CONTAINING CARBOXYLIC ACID | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1998-02-03 | — | — | US | claimed |
| WO-2016051799-A1 | 2-AMINOHYDROQUINONE DERIVATIVE AND TAU AGGREGATION INHIBITOR | 学校法人同志社 | 2016-04-07 | — | — | WO | disclosed |
| US-7506977-B1 | Plastic spectacles lens | HOPNIC LABORATORY CO., LTD. (JP) | 2009-03-24 | — | — | US | disclosed |