Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | LTC4S | Q16873 | 6/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 2/20 | 0.38 |
| ▸ | RORB | Q92753 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3914431 | 0.87 | LTB4R2 (0.42) | RXFP1SMN1; SMN2DHODHLMNATSHR | |
| SCHEMBL3926520 | 0.80 | LMNA (0.39) | HTTDHODHLMNAMAPT | |
| SCHEMBL3916848 | 0.76 | LMNA (0.42) | HTTLMNAMAPT | |
| SCHEMBL3918834 | 0.73 | DHODH (0.41) | DHODHTSHR | |
| SCHEMBL5491797 | 0.71 | CES2 (0.47) | RXFP1HTTLMNAMAPT | |
| SCHEMBL3926139 | 0.69 | LMNA (0.57) | RXFP1HTTDHODHLMNAMAPT | |
| SCHEMBL3914255 | 0.68 | TSHR (0.43) | HTTSMN1; SMN2DHODHLMNATSHR | |
| SCHEMBL3916870 | 0.68 | F2 (0.40) | SMN1; SMN2DHODHTSHR | |
| SCHEMBL4461612 | 0.65 | ATM (0.45) | RXFP1HTTSMN1; SMN2MAPT | |
| SCHEMBL17891690 | 0.65 | RXFP1 (0.43) | RXFP1HTTSMN1; SMN2LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1392642-B1 | NOVEL COMPOUNDS AS ANTI-INFLAMMATORY, IMMUNOMODULATORY AND ANTI-PROLIFERATORY AGENTS | 4SC AG (DE) | 2009-12-09 | — | — | EP | disclosed |
| EP-2093214-A1 | Novel compounds as anti-inflammatory, immunomodulatory and anti-proliferatory agents | 4SC AG (DE) | 2009-08-26 | — | — | EP | disclosed |