Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ESRRA | P11474 | 2/20 | 0.34 |
| ▸ | SCN8A | Q9UQD0 | 4/20 | 0.34 |
| ▸ | SCN10A | Q9Y5Y9 | 4/20 | 0.34 |
| ▸ | PNLIP | P16233 | 2/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3926982 | 0.87 | SLC6A2 (0.39) | SLC6A2SLC6A3SLC6A4ALDH1A1POLB | |
| SCHEMBL27692981 | 0.80 | NPC1 (0.42) | SLC6A2SLC6A3SLC6A4ALDH1A1POLB | |
| SCHEMBL1333574 | 0.79 | SLC6A2 (0.43) | SLC6A2SLC6A3SLC6A4ALDH1A1GAA | |
| SCHEMBL1333707 | 0.78 | CA1 (0.52) | SLC6A2SLC6A3SLC6A4HPGDPNLIP | |
| SCHEMBL1333750 | 0.77 | PTGDR2 (0.53) | — | |
| SCHEMBL3248291 | 0.74 | SCN9A (0.37) | SLC6A2SLC6A3SLC6A4ALDH1A1POLB | |
| SCHEMBL5755250 | 0.74 | KDM4E (0.46) | ALDH1A1POLBGAAHPGDL3MBTL1 | |
| SCHEMBL28365688 | 0.74 | MAPK1 (0.38) | ALDH1A1GAA | |
| SCHEMBL1959633 | 0.74 | MAOA (0.46) | SLC6A2SLC6A3ALDH1A1POLBGAA | |
| SCHEMBL1964539 | 0.72 | CYP3A4 (0.56) | SLC6A2SLC6A3SLC6A4ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1660431-B1 | PHENOXYACETIC ACID DERIVATIVES | ASTRAZENECA AB (SE) | 2009-04-01 | — | — | EP | disclosed |
| EP-1660431-A2 | PHENOXYACETIC ACID DERIVATIVES | Astrazeneca AB (SE) | 2006-05-31 | — | — | EP | disclosed |
| WO-2005018529-A2 | PHENOXIACETIC ACID DERIVATIVES | ASTRAZENECA AB (SE) | 2005-03-03 | — | — | WO | disclosed |