SCHEMBL392820

SCHEMBL392820

FC(F)(F)c1c[nH]cn1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28918481 0.76
SCHEMBL1948912 0.69
SCHEMBL12012896 0.67
SCHEMBL12993678 0.66 SHBG (0.32)
SCHEMBL19859581 0.66 JAK2 (0.33)
SCHEMBL16820199 0.64
SCHEMBL3531456 0.64 DGAT1 (0.34)
SCHEMBL10250077 0.64
SCHEMBL6407483 0.63 KDM1A (0.39)
SCHEMBL1931544 0.62 TRPV4 (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 841 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117285985-A Low-dynamic surface tension insulating layer buffer cleaning liquid and preparation method and application thereof 四川格林达电子材料有限公司 2023-12-26 CN claimed
CN-117165078-A Cyanate resin with low dielectric loss suitable for winding forming process, preparation method and application 中国科学院宁波材料技术与工程研究所 2023-12-05 CN claimed
CN-113745539-B Fluorine-containing non-noble metal oxygen reduction electrocatalyst and preparation method and application thereof 大连理工大学 2022-11-22 CN claimed
CN-113745539-A Fluorine-containing non-noble metal oxygen reduction electrocatalyst and preparation method and application thereof 大连理工大学 2021-12-03 CN claimed
CN-111821811-A Novel dicationic ionic liquid containing ether bond and nitrogen heterocycle and method for trapping sulfur dioxide by using same 天津大学 2020-10-27 CN claimed
CN-108714224-B PH response type19F magnetic resonance imaging nano probe and preparation method thereof 北京化工大学 2020-06-16 CN claimed
US-10224485-B2 Process for preparing a crystalline organic semiconductor material BASF SE (DE) 2019-03-05 US claimed
CN-108714224-A A kind of pH response types19F magnetic resonance imaging nano-probes and preparation method thereof 北京化工大学 2018-10-30 CN claimed
US-20170012208-A1 ORGANIC SEMICONDUCTOR FORMULATIONS USINVEST LLC 2017-01-12 US claimed
CN-103224535-A Metal or ligand replacement method for construction of mixed metal or mixed ligand zeolitic imidazolate frameworks (ZIFs) DALIAN CHEMICAL PHYSICS INST 2013-07-31 CN claimed
US-20050080260-A1 Preparation of prodrugs for selective drug delivery LUMINIDE 2005-04-14 US claimed
EP-0880504-A1 HETEROCYCLO-SUBSTITUTED IMIDAZOLES FOR THE TREATMENT OF INFLAMMATION G.D. SEARLE &amp; CO. (US) 1998-12-02 EP claimed
EP-0843549-A1 COMPOSITIONS COMPRISING A CYCLOOXYGENASE-2 INHIBITOR AND A LEUKOTRIENE A 4? HYDROLASE INHIBITOR G.D. SEARLE &amp; CO. (US) 1998-05-27 EP claimed
EP-0833622-A1 COMPOSITIONS COMPRISING A CYCLOOXYGENASE-2 INHIBITOR AND A 5-LIPOXYGENASE INHIBITOR G.D. SEARLE &amp; CO. (US) 1998-04-08 EP claimed
EP-0833664-A1 COMBINATION OF A CYCLOOXYGENASE-2 INHIBITOR AND A LEUKOTRIENE B 4? RECEPTOR ANTAGONIST FOR THE TREATMENT OF INFLAMMATIONS G.D. SEARLE &amp; CO. (US) 1998-04-08 EP claimed
WO-1997027181-A1 HETEROCYCLO-SUBSTITUTED IMIDAZOLES FOR THE TREATMENT OF INFLAMMATION G.D. SEARLE & CO. (US) 1997-07-31 WO claimed
WO-1996041645-A1 COMBINATION OF A CYCLOOXYGENASE-2 INHIBITOR AND A LEUKOTRIENE B4 RECEPTOR ANTAGONIST FOR THE TREATMENT OF INFLAMMATIONS G.D. SEARLE & CO. (US) 1996-12-27 WO claimed
WO-1996041625-A1 COMPOSITIONS COMPRISING A CYCLOOXYGENASE-2 INHIBITOR AND A LEUKOTRIENE A4 HYDROLASE INHIBITOR G.D. SEARLE & CO. (US) 1996-12-27 WO claimed
WO-1996041626-A1 COMPOSITIONS COMPRISING A CYCLOOXYGENASE-2 INHIBITOR AND A 5-LIPOXYGENASE INHIBITOR G.D. SEARLE & CO. (US) 1996-12-27 WO claimed
CN-85104392-A The preparation method of quinolone inotropic agents 1986-12-24 CN claimed