Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IAPP | P10997 | 4/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.41 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28602299 | 0.76 | ACLY (0.33) | FFAR1MEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL28612715 | 0.70 | IAPP (0.42) | IAPPCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL3515237 | 0.70 | PLA2G2A (0.76) | FFAR1PLA2G2APLA2G5MEN1KMT2A | |
| SCHEMBL28715519 | 0.67 | IAPP (0.47) | IAPPMEN1KMT2ACYP3A4HPGD | |
| SCHEMBL31383411 | 0.67 | IAPP (0.55) | IAPPCYP1A2CYP3A4CYP2C8CYP2C9 | |
| SCHEMBL28700300 | 0.67 | IAPP (0.38) | IAPPMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL18371595 | 0.66 | CYP19A1 (0.53) | MEN1KMT2ACYP3A4HPGDNPC1 | |
| SCHEMBL18391825 | 0.65 | CYP19A1 (0.51) | MEN1KMT2ACYP3A4HPGDNPC1 | |
| SCHEMBL1538218 | 0.65 | ALDH1A1 (0.58) | IAPPHPGDNPC1MAPK1RAB9A | |
| SCHEMBL28602301 | 0.65 | IAPP (0.39) | IAPPFFAR1PLA2G2APLA2G5MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009011870-A1 | REDUCTION OF BETA-AMYLOID LEVELS BY TREATMENT WITH THE SMALL MOLECULE DIFFERENTIATION-INDUCING FACTOR | THE GENERAL HOSPITAL CORPORATION (US) | 2009-01-22 | — | — | WO | disclosed |