Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.34 |
| ▸ | AGER | Q15109 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.32 |
| ▸ | DHODH | Q02127 | 1/20 | 0.32 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.31 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.31 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.31 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.31 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.31 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | STAT3 | P40763 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13160700 | 0.77 | GAA (0.43) | KMT2AALDH1A1MEN1AGERGAA | |
| SCHEMBL3937816 | 0.76 | CA12 (0.36) | KMT2AALDH1A1MEN1CYP24A1AGER | |
| SCHEMBL3928429 | 0.76 | CA12 (0.36) | KMT2AALDH1A1MEN1CYP24A1AGER | |
| SCHEMBL3933771 | 0.76 | — | — | |
| SCHEMBL30661638 | 0.76 | CA2 (0.43) | KMT2AALDH1A1MEN1AGERPPARG | |
| SCHEMBL11264990 | 0.75 | GAA (0.38) | KMT2AALDH1A1MEN1AGERDHODH | |
| SCHEMBL5468126 | 0.73 | GAA (0.42) | KMT2AALDH1A1MEN1AGERPPARG | |
| SCHEMBL5468129 | 0.73 | GAA (0.42) | KMT2AALDH1A1MEN1AGERPPARG | |
| SCHEMBL22105991 | 0.71 | ALDH1A1 (0.42) | KMT2AALDH1A1MEN1CYP24A1AGER | |
| SCHEMBL1545381 | 0.70 | CA2 (0.47) | KMT2AALDH1A1MEN1AGERPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009011551-A2 | PROCESS FOR THE EFFICIENT PREPARATION OF 3-HYDROXY PYRROLIDINE AND DERIVATIVES THEREOF | RSTECH CORPORATION (KR) | 2009-01-22 | — | — | WO | disclosed |