Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | USP2 | O75604 | 1/20 | 0.64 |
| ▸ | HPGD | P15428 | 1/20 | 0.64 |
| ▸ | HTR1A | P08908 | 1/20 | 0.58 |
| ▸ | HTR1B | P28222 | 1/20 | 0.58 |
| ▸ | HTR2A | P28223 | 1/20 | 0.58 |
| ▸ | HTR2C | P28335 | 1/20 | 0.58 |
| ▸ | HTR2B | P41595 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3940443 | 0.86 | NPSR1 (0.64) | NPSR1ALDH1A1USP2HPGDHTR1A | |
| SCHEMBL13961306 | 0.86 | NPSR1 (0.50) | NPSR1ALDH1A1USP2HPGDTSHR | |
| SCHEMBL13960765 | 0.85 | MAPT (0.58) | ALDH1A1HPGDMAPT | |
| SCHEMBL13961091 | 0.84 | CCR5 (0.67) | NPSR1ALDH1A1USP2HPGDHTR1A | |
| SCHEMBL3938078 | 0.84 | NPSR1 (0.61) | NPSR1ALDH1A1USP2HPGDHTR1A | |
| SCHEMBL13746186 | 0.84 | NPSR1 (0.72) | NPSR1ALDH1A1USP2HPGDHTR1A | |
| SCHEMBL3939743 | 0.83 | NPSR1 (0.60) | NPSR1ALDH1A1USP2HPGDHTR1A | |
| SCHEMBL3938427 | 0.83 | CCR5 (0.53) | NPSR1ALDH1A1HTR1AHTR2ATSHR | |
| SCHEMBL2469546 | 0.82 | ALDH1A1 (0.86) | NPSR1ALDH1A1USP2HPGDHTR1A | |
| SCHEMBL29675228 | 0.82 | ALDH1A1 (0.86) | NPSR1ALDH1A1USP2HPGDHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009010480-A1 | 1-{2-[(DIPHENYL)AMINO]-ETHYL}-PIPERIDINE-4-CARBOXYLIC ACID BENZYLAMIDE DERIVATIVES AND RELATED COMPOUNDS AS CCR5 AGONISTS FOR THE TREATMENT OF IMMUNE AND INFLAMMATORY DISEASES | EUROSCREEN S.A. (BE) | 2009-01-22 | — | — | WO | disclosed |