Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ACLY | P53396 | 2/20 | 0.36 |
| ▸ | HTR6 | P50406 | 7/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.34 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.34 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.34 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.34 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.34 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | NPY1R | P25929 | 1/20 | 0.33 |
| ▸ | NPY2R | P49146 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3555537 | 0.92 | ACLY (0.38) | AGTR1CYP1A2CYP2D6CYP2C19ACLY | |
| SCHEMBL3565645 | 0.90 | ACLY (0.41) | CYP1A2CYP2D6CYP2C19ACLYHTR6 | |
| SCHEMBL3556846 | 0.90 | ACLY (0.47) | ACLYHTR6KDM4EALDH1A1PSEN1 | |
| SCHEMBL3564373 | 0.90 | HTR6 (0.43) | ACLYHTR6HTR7 | |
| SCHEMBL3564671 | 0.89 | HTR6 (0.46) | HTR6HTR7 | |
| SCHEMBL3562373 | 0.89 | HTR6 (0.43) | AGTR1HTR6KDM4EALDH1A1HTR7 | |
| SCHEMBL3560725 | 0.88 | HTR6 (0.40) | CYP1A2CYP2D6CYP2C19HTR6KDM4E | |
| SCHEMBL3935893 | 0.86 | ACLY (0.35) | CYP1A2CYP2D6CYP2C19ACLYKDM4E | |
| SCHEMBL3562490 | 0.85 | ACLY (0.35) | CYP1A2CYP2D6CYP2C19ACLYHTR6 | |
| SCHEMBL3929369 | 0.84 | AGTR1 (0.56) | AGTR1HTR6ALDH1A1PSEN1PSEN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1567492-B1 | N-ARYLSULFONYL-3-AMINOALKOXYINDOLES | SUVEN LIFE SCIENCES LTD (IN) | 2013-05-22 | — | — | EP | claimed |
| US-7507835-B2 | N-arylsulfonyl-3-aminoalkoxyindoles | SUVEN LIFE SCIENCES LTD. (IN) | 2009-03-24 | — | — | US | claimed |
| EP-1567492-B1 | N-ARYLSULFONYL-3-AMINOALKOXYINDOLES | SUVEN LIFE SCIENCES LTD (IN) | 2013-05-22 | — | — | EP | disclosed |