SCHEMBL3929454

SCHEMBL3929454

[O]c1ccc(C(c2cc[c]cc2)(C(F)(F)F)C(F)(F)F)cc1

nearest known ligand 0.45

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.45
ESR2 Q92731 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2338854 0.87 ESR1 (0.50) ESR1ESR2
SCHEMBL3324812 0.78 TSHR (0.44) ESR1ESR2
SCHEMBL8150717 0.74 ESR1 (0.41) ESR1ESR2
SCHEMBL17389287 0.74 ESR1 (0.41) ESR1ESR2
SCHEMBL28255471 0.69 ESR1 (0.59) ESR1ESR2
SCHEMBL744464 0.68
SCHEMBL662971 0.67
SCHEMBL698786 0.67
SCHEMBL8994533 0.67 PGK1 (0.33) ESR1ESR2
SCHEMBL2092987 0.67 RORC (0.35) ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2063471-B1 Organic field effect transistor HITACHI LTD (JP) 2012-10-03 EP claimed
US-20090134386-A1 Organic Field Effect Transistor HITACHI, LTD. (JP) 2009-05-28 US claimed
EP-2063471-A1 Organic field effect transistor Hitachi Ltd. (JP) 2009-05-27 EP claimed
EP-2063471-B1 Organic field effect transistor HITACHI LTD (JP) 2012-10-03 EP disclosed
US-20090134386-A1 Organic Field Effect Transistor HITACHI, LTD. (JP) 2009-05-28 US disclosed
EP-2063471-A1 Organic field effect transistor Hitachi Ltd. (JP) 2009-05-27 EP disclosed