Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGK1 | P00558 | 1/20 | 0.33 |
| ▸ | PGK2 | P07205 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2092987 | 0.78 | RORC (0.35) | PGK1PGK2ESR1ESR2CES2 | |
| SCHEMBL186746 | 0.77 | CES2 (0.52) | CES2CES1 | |
| SCHEMBL18242205 | 0.74 | PGK1 (0.31) | PGK1PGK2ESR1ESR2CES2 | |
| SCHEMBL8608040 | 0.72 | ESR1 (0.64) | ESR1ESR2MAPTHSD17B10 | |
| SCHEMBL18243912 | 0.72 | LMNA (0.31) | PGK1PGK2ESR1ESR2 | |
| SCHEMBL11546152 | 0.71 | TSHR (0.58) | PGK1PGK2CES1 | |
| SCHEMBL16046946 | 0.69 | CA1 (0.56) | HSD17B10CES1 | |
| SCHEMBL3929454 | 0.67 | ESR1 (0.45) | ESR1ESR2 | |
| SCHEMBL22242853 | 0.67 | PTPN5 (0.47) | GAAMAPTHSD17B10 | |
| SCHEMBL9408539 | 0.67 | ALDH1A1 (0.40) | PGK1PGK2ESR1ESR2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5567597-A | DIAGNOSING THE DISEASE BY DETECTING, MEASURING THE LIPASE, PHOSPHOLIPASE, ESTERASE, PROTEASE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1996-10-22 | — | — | US | disclosed |
| US-5427919-A | Therapy, analysis substrates | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1995-06-27 | — | — | US | disclosed |
| US-5352673-A | Administering to inactivate or inhibit phospholipase A | REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE A CORP. OF CALIFORNIA | 1994-10-04 | — | — | US | disclosed |
| US-5308766-A | Hydrolytic enzyme inhibitors/inactivators and methods for using same | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1994-05-03 | — | — | US | disclosed |
| WO-1992022289-A1 | NOVEL PHOSPHOLIPASE A2 INHIBITORS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1992-12-23 | — | — | WO | disclosed |