Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | INMT | O95050 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2420911 | 0.98 | — | — | |
| Iodide SCHEMBL11445662 | 0.96 | — | — | |
| Bromide SCHEMBL8732340 | 0.92 | ALDH1A1 (0.37) | — | |
| Bromide SCHEMBL7193301 | 0.92 | ALDH1A1 (0.37) | — | |
| Bromide SCHEMBL9154612 | 0.92 | ALDH1A1 (0.37) | — | |
| SCHEMBL2363930 | 0.92 | ALDH1A1 (0.32) | — | |
| SCHEMBL9778326 | 0.90 | PTGS1 (0.34) | — | |
| SCHEMBL11445710 | 0.90 | PTGS1 (0.34) | — | |
| SCHEMBL28784387 | 0.90 | PTGS1 (0.34) | — | |
| SCHEMBL11135652 | 0.90 | PTGS1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2044013-B1 | PROCESS FOR PRODUCING 2-HYDROXY-4-(METHYLTHIO)BUTYRATE COMPOUNDS AND INTERMEDIATES THEREOF | SUMITOMO CHEMICAL CO (JP) | 2013-05-29 | — | — | EP | disclosed |
| CN-101489998-B | Process for producing 2-hydroxy-4- (methylthio) butanoic acid or butyrate compound and intermediate thereof | SUMITOMO CO LTD | 2013-01-02 | — | — | CN | disclosed |
| CN-102702046-A | Process for producing 2-hydroxy-4-(methylthio) butyrate compounds and intermediates thereof | SUMITOMO CHEMICAL CO | 2012-10-03 | — | — | CN | disclosed |
| US-20090192328-A1 | PROCESS FOR PRODUCING 2-HYDROXY-4-(METHLTHIO)BUTYRATE COMPOUNDS AND INTERMEDIATES THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-07-30 | — | — | US | disclosed |
| CN-101489998-A | Process for producing 2-hydroxy-4- (methylthio) butanoic acid or butyrate compound and intermediate thereof | SUMITOMO CHEMICAL CO (JP) | 2009-07-22 | — | — | CN | disclosed |
| EP-2044013-A1 | PROCESS FOR PRODUCING 2-HYDROXY-4-(METHYLTHIO)BUTYRATE COMPOUNDS AND INTERMEDIATES THEREOF | Sumitomo Chemical Company, Limited (JP) | 2009-04-08 | — | — | EP | disclosed |
| WO-2008010609-A1 | PROCESS FOR PRODUCING 2-HYDROXY-4-(METHYLTHIO)BUTYRATE COMPOUNDS AND INTERMEDIATES THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2008-01-24 | — | — | WO | disclosed |
| US-4775448-A | THIN FILM EVAPORATORS TO DISTIL DIHYDROXYACETONE FROM SOLVENT | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-10-04 | — | — | US | disclosed |
| EP-0245976-A1 | Process for the isolation of dihydroxyacetone | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-11-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090192328-A1 | PROCESS FOR PRODUCING 2-HYDROXY-4-(METHLTHIO)BUTYRATE COMPOUNDS AND INTERMEDIATES THEREOF | HAO2, BBOX1, HAO1 | INMT 1201/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.