SCHEMBL3931396 — predicted protein targets

Predicted protein targets (top 10)

	gene	UniProt	supporting neighbours	confidence
▸	FAAH	O00519	11/20	0.85

▸	MKNK1	Q9BUB5	4/20	0.42

▸	LMNA	P02545	2/20	0.39

▸	ALDH1A1	P00352	1/20	0.39

▸	MAPK1	P28482	1/20	0.39

▸	HTT	P42858	1/20	0.39

▸	KMT2A	Q03164	2/20	0.39

▸	RAB9A	P51151	1/20	0.39

▸	SMN1; SMN2	Q16637	1/20	0.38

▸	GPR6	P46095	1/20	0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL3942417	0.94	FAAH (0.78)	FAAHMKNK1
SCHEMBL3933876	0.93	FAAH (0.76)	FAAHMKNK1LMNAALDH1A1MAPK1
SCHEMBL3941135	0.92	FAAH (1.00)	FAAHLMNAALDH1A1MAPK1HTT
SCHEMBL3935259	0.92	FAAH (0.75)	FAAH
SCHEMBL3937394	0.92	FAAH (0.75)	FAAHMKNK1LMNAALDH1A1MAPK1
SCHEMBL3934215	0.92	FAAH (0.77)	FAAHMKNK1LMNAALDH1A1MAPK1
SCHEMBL3943571	0.92	FAAH (0.77)	FAAHMKNK1LMNAALDH1A1MAPK1
SCHEMBL3941303	0.92	FAAH (0.82)	FAAHMKNK1
SCHEMBL3936263	0.91	FAAH (0.90)	FAAHLMNAALDH1A1MAPK1HTT
SCHEMBL3942978	0.90	FAAH (0.86)	FAAHLMNAALDH1A1MAPK1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2009011904-A1	COMPOUNDS USEFUL AS FAAH MODULATORS AND USES THEREOF	RENOVIS, INC. (US)	2009-01-22	—	—	WO	disclosed