Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 11/20 | 0.76 |
| ▸ | MKNK1 | Q9BUB5 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3931396 | 0.93 | FAAH (0.85) | FAAHMKNK1LMNAALDH1A1MAPK1 | |
| SCHEMBL3937394 | 0.92 | FAAH (0.75) | FAAHMKNK1LMNAALDH1A1MAPK1 | |
| SCHEMBL3942417 | 0.91 | FAAH (0.78) | FAAHMKNK1 | |
| SCHEMBL3932480 | 0.90 | FAAH (0.83) | FAAHLMNAALDH1A1MAPK1HTT | |
| SCHEMBL3933960 | 0.90 | FAAH (0.86) | FAAHMKNK1LMNAALDH1A1MAPK1 | |
| SCHEMBL3935259 | 0.88 | FAAH (0.75) | FAAH | |
| SCHEMBL3943571 | 0.88 | FAAH (0.77) | FAAHMKNK1LMNAALDH1A1MAPK1 | |
| SCHEMBL3941303 | 0.88 | FAAH (0.82) | FAAHMKNK1 | |
| SCHEMBL3942978 | 0.87 | FAAH (0.86) | FAAHLMNAALDH1A1MAPK1HTT | |
| SCHEMBL3941135 | 0.87 | FAAH (1.00) | FAAHLMNAALDH1A1MAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009011904-A1 | COMPOUNDS USEFUL AS FAAH MODULATORS AND USES THEREOF | RENOVIS, INC. (US) | 2009-01-22 | — | — | WO | disclosed |