Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 10/20 | 0.82 |
| ▸ | MKNK1 | Q9BUB5 | 7/20 | 0.49 |
| ▸ | IGF1R | P08069 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | ALPL | P05186 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3942417 | 0.98 | FAAH (0.78) | FAAHMKNK1IGF1RPKMALPL | |
| SCHEMBL3943232 | 0.98 | FAAH (0.78) | FAAHMKNK1IGF1RPKM | |
| SCHEMBL3932545 | 0.92 | FAAH (0.79) | FAAHMKNK1IGF1RALPL | |
| SCHEMBL3931396 | 0.92 | FAAH (0.85) | FAAHMKNK1 | |
| SCHEMBL3933101 | 0.91 | FAAH (0.73) | FAAHMKNK1IGF1RALPL | |
| SCHEMBL3942587 | 0.91 | FAAH (0.78) | FAAHMKNK1 | |
| SCHEMBL3930701 | 0.91 | FAAH (0.86) | FAAHMKNK1ALPL | |
| SCHEMBL3941343 | 0.91 | FAAH (0.86) | FAAHPKMALPL | |
| SCHEMBL3942978 | 0.90 | FAAH (0.86) | FAAHPKM | |
| SCHEMBL3941135 | 0.90 | FAAH (1.00) | FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009011904-A1 | COMPOUNDS USEFUL AS FAAH MODULATORS AND USES THEREOF | RENOVIS, INC. (US) | 2009-01-22 | — | — | WO | disclosed |