Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 11/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | PRF1 | P14222 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3941306 | 0.89 | FAAH (0.65) | FAAHKMT2AALDH1A1LMNAMAPK1 | |
| SCHEMBL3938696 | 0.86 | FAAH (0.62) | FAAHKMT2AALDH1A1TRPV1POLB | |
| SCHEMBL4014500 | 0.85 | FAAH (0.64) | FAAHKMT2AALDH1A1LMNAMAPK1 | |
| SCHEMBL3937438 | 0.85 | FAAH (0.73) | FAAHALDH1A1LMNAMAPK1HTT | |
| SCHEMBL3931485 | 0.85 | FAAH (0.73) | FAAHKMT2AALDH1A1LMNAMAPK1 | |
| SCHEMBL3933627 | 0.85 | FAAH (0.73) | FAAHKMT2AALDH1A1LMNAMAPK1 | |
| SCHEMBL3933834 | 0.84 | FAAH (0.70) | FAAHKMT2AALDH1A1LMNAMAPK1 | |
| SCHEMBL3931109 | 0.84 | FAAH (0.67) | FAAHALDH1A1LMNAMAPK1HTT | |
| SCHEMBL3931080 | 0.82 | FAAH (0.75) | FAAHALDH1A1LMNAMAPK1HTT | |
| SCHEMBL3937611 | 0.82 | FAAH (0.62) | FAAHALDH1A1TRPV1GRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009011904-A1 | COMPOUNDS USEFUL AS FAAH MODULATORS AND USES THEREOF | RENOVIS, INC. (US) | 2009-01-22 | — | — | WO | disclosed |