Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 11/20 | 0.64 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | IGF1R | P08069 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3933627 | 0.87 | FAAH (0.73) | FAAHL3MBTL1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL3931801 | 0.85 | FAAH (0.66) | FAAHL3MBTL1ALDH1A1LMNAMAPK1 | |
| SCHEMBL3941306 | 0.84 | FAAH (0.65) | FAAHPFKFB3L3MBTL1CYP1A2CYP2D6 | |
| SCHEMBL3937438 | 0.84 | FAAH (0.73) | FAAHL3MBTL1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL3931485 | 0.84 | FAAH (0.73) | FAAHL3MBTL1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL3933834 | 0.83 | FAAH (0.70) | FAAHL3MBTL1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL3932389 | 0.83 | FAAH (0.72) | FAAHL3MBTL1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL3931109 | 0.82 | FAAH (0.67) | FAAHPFKFB3ALDH1A1LMNAMAPK1 | |
| SCHEMBL3938696 | 0.82 | FAAH (0.62) | FAAHL3MBTL1ALDH1A1POLBKMT2A | |
| SCHEMBL3931080 | 0.81 | FAAH (0.75) | FAAHALDH1A1LMNAMAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009011904-A1 | COMPOUNDS USEFUL AS FAAH MODULATORS AND USES THEREOF | RENOVIS, INC. (US) | 2009-01-22 | — | — | WO | disclosed |