Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 11/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3931485 | 0.89 | FAAH (0.73) | FAAHALDH1A1LMNAMAPK1HTT | |
| SCHEMBL3937438 | 0.88 | FAAH (0.73) | FAAHALDH1A1LMNAMAPK1HTT | |
| SCHEMBL3933627 | 0.88 | FAAH (0.73) | FAAHALDH1A1LMNAMAPK1HTT | |
| SCHEMBL3935806 | 0.85 | FAAH (0.78) | FAAHALDH1A1LMNAMAPK1HTT | |
| SCHEMBL3931080 | 0.85 | FAAH (0.75) | FAAHALDH1A1LMNAMAPK1HTT | |
| SCHEMBL3931801 | 0.84 | FAAH (0.66) | FAAHALDH1A1LMNAMAPK1HTT | |
| SCHEMBL3945032 | 0.84 | FAAH (0.82) | FAAHALDH1A1LMNAMAPK1HTT | |
| SCHEMBL3934237 | 0.84 | FAAH (0.76) | FAAHALDH1A1MAPK1SMN1; SMN2TSHR | |
| SCHEMBL3941306 | 0.84 | FAAH (0.65) | FAAHALDH1A1LMNAMAPK1HTT | |
| SCHEMBL3934554 | 0.84 | FAAH (0.72) | FAAHALDH1A1LMNAMAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009011904-A1 | COMPOUNDS USEFUL AS FAAH MODULATORS AND USES THEREOF | RENOVIS, INC. (US) | 2009-01-22 | — | — | WO | disclosed |