SCHEMBL393197

SCHEMBL393197

NS(=O)(=O)C1CCCCC1

nearest known ligand 0.52

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CA1 P00915 6/20 0.52
CA2 P00918 5/20 0.52
APLNR P35414 2/20 0.52
CA7 P43166 3/20 0.38
CA12 O43570 2/20 0.38
CA14 Q9ULX7 2/20 0.38
EPHX1 P07099 1/20 0.35
LOXL2 Q9Y4K0 3/20 0.34
LOX P28300 1/20 0.34
CA9 Q16790 2/20 0.33
CA5A P35218 1/20 0.33
CA5B Q9Y2D0 1/20 0.33
EPHX2 P34913 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1648801 1.00 CA1 (0.52) CA1CA2APLNRCA7CA12
SCHEMBL19479300 1.00 CA1 (0.52) CA1CA2APLNRCA7CA12
SCHEMBL21943788 1.00 CA1 (0.52) CA1CA2APLNRCA7CA12
SCHEMBL1649129 1.00 CA1 (0.52) CA1CA2APLNRCA7CA12
SCHEMBL19066054 1.00 CA1 (0.52) CA1CA2APLNRCA7CA12
SCHEMBL14462832 1.00 CA1 (0.52) CA1CA2APLNRCA7CA12
Hydrochloric Acid SCHEMBL21598754 0.97 CA1 (0.50) CA1CA2APLNRCA7CA12
SCHEMBL244348 0.97
Hydrochloric Acid SCHEMBL29086421 0.94 APLNR (0.52) CA1CA2APLNRCA7CA12
SCHEMBL636980 0.90

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1428 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4301736-B1 MACROCYCLIC COMPOUNDS AS PROTEASOME SUBUNIT BETA TYPE-5 INHIBITORS LEAD DISCOVERY CENTER GMBH (DE) 2025-10-08 EP claimed
EP-3917907-B1 MODULATORS OF POTASSIUM ION CHANNELS AND USES THEREOF UNIV DEGLI STUDI DI SALERNO (IT) 2025-05-21 EP claimed
EP-4073044-B1 NEW BRAF INHIBITORS AS PARADOX BREAKERS HOFFMANN LA ROCHE (CH) 2025-02-19 EP claimed
CN-119233829-A Pharmaceutical composition for preventing, inhibiting or treating symptoms associated with pseudoallergy 学校法人高崎健康福祉大学 2024-12-31 CN claimed
US-20240415819-A1 MACROCYCLIC COMPOUNDS AS PROTEASOME SUBUNIT BETA TYPE-5 INHIBITORS QLi5 Therapeutics AG (DE) 2024-12-19 US claimed
CN-118851955-A 2-Arylmethoxyiminocyclohexane sulfonamide compound, and preparation method and application thereof 沈阳农业大学 2024-10-29 CN claimed
CN-118401505-A Heterocyclic compounds as SHP2 inhibitors, compositions comprising the same, and methods of use thereof 捷思英达控股有限公司 2024-07-26 CN claimed
CN-118176003-A Medicaments comprising P2X4 receptor antagonists for the prevention or treatment of nociceptive pain and/or visceral pain 日本化学药品株式会社 2024-06-11 CN claimed
CN-118019551-A Preventive or therapeutic agent for respiratory diseases 日本化学药品株式会社 2024-05-10 CN claimed
CN-117624890-A Preparation process of flame-retardant HMMM resin for improving rubber vulcanization speed 江苏国立化工科技有限公司 2024-03-01 CN claimed
US-20050054534-A1 Substituted benzoylcyclohexane diones for use as herbicides MULLER KLAUS-HELMUT (DE) 2005-03-10 US claimed
EP-0906291-B1 SUBSTITUTED PHENYL URACILS BAYER CROPSCIENCE AG (DE) 2005-03-09 EP claimed
EP-1244634-B1 SUBSTITUTED BENZOYLCYCLOHEXANE DIONES FOR USE AS HERBICIDES BAYER CROPSCIENCE AG (DE) 2004-03-17 EP claimed
US-6245714-B1 HERBICIDES BAYER AKTIENGESELLSCHAFT (DE) 2001-06-12 US claimed
EP-0906291-A1 SUBSTITUTED PHENYL URACILS BAYER AG (DE) 1999-04-07 EP claimed
WO-1997045418-A1 SUBSTITUTED PHENYL URACILS BAYER AKTIENGESELLSCHAFT (DE) 1997-12-04 WO claimed
EP-0373951-B1 PREPARATION OF 2,3-TRANS-1,4-BRIDGED CYCLOHEXANE SULFONAMIDE DERIVATIVES AND THEIR USE SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. (JP) 1993-03-24 EP claimed
US-5120865-A PREPARATION OF 2,3-TRANS-1,4-BRIDGED CYCLOHEXANE SULFONAMIDE DERIVATIVES SHIONOGI & CO., LTD. (JP) 1992-06-09 US claimed
EP-0373951-A1 Preparation of 2,3-trans-1,4-bridged cyclohexane sulfonamide derivatives and their use SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. (JP) 1990-06-20 EP claimed
US-4294641-A Heat transfer sheets REED KENNETH JAMES (GB) 1981-10-13 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050054534-A1 Substituted benzoylcyclohexane diones for use as herbicides DDT, CYP1B1, CYP1A1 CA1 784/4885CA2 356/4885APLNR 3654/4885
US-20240415819-A1 MACROCYCLIC COMPOUNDS AS PROTEASOME SUBUNIT BETA TYPE-5 INHIBITORS PSMB5, PSMA5, PSMB1 CA1 2703/4885CA2 4423/4885APLNR 4364/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.