Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 6/20 | 0.52 |
| ▸ | CA2 | P00918 | 5/20 | 0.52 |
| ▸ | APLNR | P35414 | 2/20 | 0.52 |
| ▸ | CA7 | P43166 | 3/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | LOXL2 | Q9Y4K0 | 3/20 | 0.34 |
| ▸ | LOX | P28300 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL393197 | 1.00 | CA1 (0.52) | CA1CA2APLNRCA7CA12 | |
| SCHEMBL19479300 | 1.00 | CA1 (0.52) | CA1CA2APLNRCA7CA12 | |
| SCHEMBL21943788 | 1.00 | CA1 (0.52) | CA1CA2APLNRCA7CA12 | |
| SCHEMBL1649129 | 1.00 | CA1 (0.52) | CA1CA2APLNRCA7CA12 | |
| SCHEMBL19066054 | 1.00 | CA1 (0.52) | CA1CA2APLNRCA7CA12 | |
| SCHEMBL14462832 | 1.00 | CA1 (0.52) | CA1CA2APLNRCA7CA12 | |
| Hydrochloric Acid SCHEMBL21598754 | 0.97 | CA1 (0.50) | CA1CA2APLNRCA7CA12 | |
| SCHEMBL244348 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL29086421 | 0.94 | APLNR (0.52) | CA1CA2APLNRCA7CA12 | |
| SCHEMBL636980 | 0.90 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113226310-B | 15-PGDH inhibitors | 杏林制药株式会社 | 2024-03-19 | — | — | CN | disclosed |
| US-20230082516-A1 | 15-PGDH INHIBITOR | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2023-03-16 | — | — | US | disclosed |
| US-11299513-B2 | Cyclative release of peptidic compounds | CIRCLE PHARMA, INC. (US) | 2022-04-12 | — | — | US | disclosed |
| EP-3922247-A1 | 15-PGDH INHIBITOR | Kyorin Pharmaceutical Co., Ltd. (JP) | 2021-12-15 | — | — | EP | disclosed |
| EP-3917911-A1 | 15-PGDH INHIBITORS | Kyorin Pharmaceutical Co., Ltd. (JP) | 2021-12-08 | — | — | EP | disclosed |
| CN-113226310-A | 15-PGDH inhibitors | 杏林制药株式会社 | 2021-08-06 | — | — | CN | disclosed |
| WO-2020223551-A1 | INHIBITING OTUB1 | INTEGRAL EARLY DISCOVERY, INC. (US) | 2020-11-05 | — | — | WO | disclosed |
| WO-2020160151-A1 | 15-PGDH INHIBITORS | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2020-08-06 | — | — | WO | disclosed |
| WO-2020145250-A1 | 15-PGDH INHIBITOR | 杏林製薬株式会社 | 2020-07-16 | — | — | WO | disclosed |
| US-20200207803-A1 | CYCLATIVE RELEASE OF PEPTIDIC COMPOUNDS | CIRCLE PHARMA, INC. | 2020-07-02 | — | — | US | disclosed |
| US-20130023563-A1 | AMIDINOANILINE DERIVATIVE | AJINOMOTO CO., INC. (JP) | 2013-01-24 | — | — | US | disclosed |
| US-8227506-B2 | Benzamidine compound | AJINOMOTO., INC. (JP) | 2012-07-24 | — | — | US | disclosed |
| US-20110172416-A1 | AMIDINE DERIVATIVE | AJINOMOTO CO., INC. (JP) | 2011-07-14 | — | — | US | disclosed |
| EP-2311810-A1 | AMIDINE DERIVATIVE | Ajinomoto Co., Inc. (JP) | 2011-04-20 | — | — | EP | disclosed |
| US-20100105731-A2 | NOVEL BENZAMIDINE COMPOUND | AJINOMOTO CO., INC. (JP) | 2010-04-29 | — | — | US | disclosed |
| US-20100016319-A1 | ARYLMETHYLENE UREA DERIVATIVE AND USE THEREOF | TORAY INDUSTRIES, INC. A CORPORATION OF JAPAN (JP) | 2010-01-21 | — | — | US | disclosed |
| EP-1970375-A1 | ARYLMETHYLENE UREA DERIVATIVE AND USE THEREOF | TORAY INDUSTRIES, INC. (JP) | 2008-09-17 | — | — | EP | disclosed |
| US-20080021065-A1 | NOVEL BENZAMIDINE COMPOUND | AJINOMOTO CO. INC (JP) | 2008-01-24 | — | — | US | disclosed |
| CN-101076519-A | Amide compound and thrombopoietin receptor activator | NISSAN CHEMICAL IND LTD (JP) | 2007-11-21 | — | — | CN | disclosed |
| EP-1847527-A1 | NOVEL BENZAMIDINE COMPOUND | Ajinomoto Co., Inc. (JP) | 2007-10-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230082516-A1 | 15-PGDH INHIBITOR | UGDH, HPGD, GCDH | CA1 3243/4885CA2 1328/4885APLNR 3207/4885 |
| US-20100105731-A2 | NOVEL BENZAMIDINE COMPOUND | SERPINC1, F11, TFPI | CA1 2306/4885CA2 1771/4885APLNR 3129/4885 |
| US-11299513-B2 | Cyclative release of peptidic compounds | VIP, FURIN, PTMS | CA1 347/4885CA2 1605/4885APLNR 354/4885 |
| US-20130023563-A1 | AMIDINOANILINE DERIVATIVE | F11, SERPINC1, F8 | CA1 2563/4885CA2 1963/4885APLNR 1113/4885 |
| US-20100016319-A1 | ARYLMETHYLENE UREA DERIVATIVE AND USE THEREOF | UROD, UTS2R, SLC14A1 | CA1 4255/4885CA2 3239/4885APLNR 3214/4885 |
| US-20110172416-A1 | AMIDINE DERIVATIVE | SERPINC1, F12, F11 | CA1 2911/4885CA2 1781/4885APLNR 449/4885 |
| US-20200207803-A1 | CYCLATIVE RELEASE OF PEPTIDIC COMPOUNDS | VIP, FURIN, PTMS | CA1 347/4885CA2 1605/4885APLNR 354/4885 |
| US-20080021065-A1 | NOVEL BENZAMIDINE COMPOUND | SERPINC1, F11, TFPI | CA1 2306/4885CA2 1771/4885APLNR 3129/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.