Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL9 | O00512 | 8/20 | 0.58 |
| ▸ | CTNNB1 | P35222 | 8/20 | 0.58 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | USP5 | P45974 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3928444 | 0.90 | BCL9 (0.55) | BCL9CTNNB1HSD11B1KMT2AMEN1 | |
| SCHEMBL3932070 | 0.89 | ALDH1A1 (0.50) | BCL9CTNNB1KMT2AMEN1ALDH1A1 | |
| SCHEMBL3930676 | 0.89 | BCL9 (0.49) | BCL9CTNNB1KMT2AMEN1USP5 | |
| SCHEMBL3941700 | 0.89 | BCL9 (0.54) | BCL9CTNNB1KMT2AMEN1ALDH1A1 | |
| SCHEMBL3937652 | 0.88 | MEN1 (0.50) | BCL9CTNNB1HSD11B1KMT2AMEN1 | |
| SCHEMBL3941517 | 0.87 | MAPT (0.55) | BCL9CTNNB1KMT2AMEN1ALDH1A1 | |
| SCHEMBL4110985 | 0.87 | SMN1; SMN2 (0.48) | BCL9CTNNB1KMT2AMEN1USP5 | |
| SCHEMBL3929084 | 0.87 | MAPT (0.55) | BCL9CTNNB1KMT2AMEN1ALDH1A1 | |
| SCHEMBL3938045 | 0.87 | MAPT (0.55) | BCL9CTNNB1KMT2AMEN1ALDH1A1 | |
| SCHEMBL14366755 | 0.87 | MEN1 (0.48) | BCL9CTNNB1KMT2AMEN1USP5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2044017-A2 | SUBSTITUTED PHENYL ACETIC ACIDS AS DP-2 ANTAGONISTS | ICOS CORPORATION (US) | 2009-04-08 | — | — | EP | claimed |
| WO-2007146838-A2 | SUBSTITUTED PHENYL ACETIC ACIDS AS DP-2 ANTAGONISTS | ICOS CORPORATION (US) | 2007-12-21 | — | — | WO | claimed |
| EP-2044017-A2 | SUBSTITUTED PHENYL ACETIC ACIDS AS DP-2 ANTAGONISTS | ICOS CORPORATION (US) | 2009-04-08 | — | — | EP | disclosed |
| WO-2007146838-A2 | SUBSTITUTED PHENYL ACETIC ACIDS AS DP-2 ANTAGONISTS | ICOS CORPORATION (US) | 2007-12-21 | — | — | WO | disclosed |
| WO-2007146838-A2 | SUBSTITUTED PHENYL ACETIC ACIDS AS DP-2 ANTAGONISTS | ICOS CORPORATION (US) | 2007-12-21 | — | — | WO | disclosed |