Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 11/20 | 0.79 |
| ▸ | GBA1 | P04062 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3943266 | 0.92 | FAAH (0.82) | FAAHGBA1HSD11B1TRPV1CNR1 | |
| SCHEMBL3944150 | 0.89 | FAAH (0.70) | FAAHHSD11B1TRPV1CNR1 | |
| SCHEMBL3934243 | 0.89 | FAAH (0.83) | FAAHHTTTP53MAPT | |
| SCHEMBL3941135 | 0.89 | FAAH (1.00) | FAAHGBA1HTT | |
| SCHEMBL3939389 | 0.87 | FAAH (0.83) | FAAHGBA1HTTMAPT | |
| SCHEMBL3939612 | 0.87 | FAAH (0.83) | FAAHGBA1HTT | |
| SCHEMBL3932908 | 0.87 | FAAH (0.83) | FAAHKDM4EHTTMAPT | |
| SCHEMBL3935259 | 0.87 | FAAH (0.75) | FAAHGBA1HSD11B1TRPV1CNR1 | |
| SCHEMBL3942978 | 0.87 | FAAH (0.86) | FAAHGBA1HTT | |
| SCHEMBL3936607 | 0.86 | FAAH (0.68) | FAAHCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009011904-A1 | COMPOUNDS USEFUL AS FAAH MODULATORS AND USES THEREOF | RENOVIS, INC. (US) | 2009-01-22 | — | — | WO | disclosed |