Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.31 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.31 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28845576 | 0.88 | L3MBTL1 (0.39) | TSHRHSD17B10MGAMGAASI | |
| SCHEMBL8365675 | 0.83 | TSHR (0.36) | TSHRHSD17B10MGAMGAASI | |
| SCHEMBL3676083 | 0.82 | TSHR (0.42) | TSHRHSD17B10MGAMGAASI | |
| SCHEMBL3676085 | 0.82 | TSHR (0.42) | TSHRHSD17B10MGAMGAASI | |
| SCHEMBL28243 | 0.81 | TSHR (0.50) | TSHRHSD17B10MGAMGAASI | |
| SCHEMBL17264301 | 0.81 | TSHR (0.48) | TSHRHSD17B10MGAMGAASI | |
| SCHEMBL20377437 | 0.80 | TSHR (0.52) | TSHRHSD17B10MGAMGAASI | |
| SCHEMBL9319754 | 0.80 | GPR84 (0.41) | TSHRHSD17B10MGAMGAASI | |
| SCHEMBL1171425 | 0.80 | GPR84 (0.41) | TSHRHSD17B10MGAMGAASI | |
| SCHEMBL9169806 | 0.80 | SLC22A6 (0.52) | GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009007814-A1 | INHIBITORS OF CARBONIC ANHYDRASE | PFIZER INC. (US) | 2009-01-15 | — | — | WO | disclosed |