SCHEMBL3932380

SCHEMBL3932380

CCC[Si](OCC)(OCC)OCCNC(=O)c1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 6/20 0.55
HPGD P15428 4/20 0.54
NPC1 O15118 7/20 0.52
RAB9A P51151 7/20 0.52
NAAA Q02083 1/20 0.52
RECQL P46063 1/20 0.49
NPSR1 Q6W5P4 1/20 0.48
POLB P06746 2/20 0.48
LMNA P02545 1/20 0.48
ALDH1A1 P00352 3/20 0.47
CYP1A2 P05177 1/20 0.47
CYP3A4 P08684 1/20 0.47
CYP2C9 P11712 1/20 0.47
CYP2C19 P33261 1/20 0.47
PRSS1 P07477 1/20 0.47
CTSG P08311 1/20 0.47
CTRB1 P17538 1/20 0.47
CMA1 P23946 1/20 0.47
MAPT P10636 2/20 0.46
NFKB1 P19838 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29127798 0.84 NAAA (0.60) SMN1; SMN2HPGDNPC1RAB9ANAAA
Benzophenone SCHEMBL6035243 0.81 ALDH1A1 (0.48) SMN1; SMN2HPGDNPC1RAB9ARECQL
SCHEMBL9980885 0.80 NAAA (0.55) SMN1; SMN2HPGDNPC1RAB9ANAAA
SCHEMBL731383 0.77 SMN1; SMN2 (0.77) SMN1; SMN2HPGDNPC1RAB9ANAAA
SCHEMBL12445445 0.76 SMN1; SMN2 (0.81) SMN1; SMN2HPGDNPC1RAB9ANAAA
SCHEMBL364448 0.75 HPGD (0.87) SMN1; SMN2HPGDNPC1RAB9ANAAA
SCHEMBL334957 0.75 NAAA (0.73) SMN1; SMN2HPGDNPC1RAB9ANAAA
Benzene SCHEMBL28248159 0.75 NAAA (0.73) SMN1; SMN2HPGDNPC1RAB9ANAAA
SCHEMBL16361209 0.75 SMN1; SMN2 (0.84) SMN1; SMN2HPGDNPC1RAB9ANAAA
SCHEMBL2855125 0.74 POLB (0.57) SMN1; SMN2NPC1RAB9APOLBLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7524446-B2 Method for manufacturing a composite tire of polyurethane tread and radial carcase HANGZHOU HANMA TYRE TECHNOLOGY LTD. (CN) 2009-04-28 US disclosed
EP-1529788-B1 Method for manufacturing a composite tire of polyurethane tread and radial carcase HANGZHOU HANMA TYRE TECHNOLOGY (CN) 2007-07-25 EP disclosed
EP-1529788-A1 Method for manufacturing a composite tire of polyurethane tread and radial carcase Zhejiang Forlong Rubber&Chemicals (Group) Co.Ltd (CN) 2005-05-11 EP disclosed
US-20050092424-A1 Method for manufacturing a composite tire of polyurethane tread and radial carcase BESTIRE (XINXING) NEW MATERIAL TECHNOLOGY CO., LTD. (CN) 2005-05-05 US disclosed