Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.77 |
| ▸ | HPGD | P15428 | 6/20 | 0.64 |
| ▸ | NPC1 | O15118 | 5/20 | 0.63 |
| ▸ | RAB9A | P51151 | 5/20 | 0.63 |
| ▸ | NAMPT | P43490 | 1/20 | 0.59 |
| ▸ | NAAA | Q02083 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.56 |
| ▸ | CTSG | P08311 | 1/20 | 0.56 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.56 |
| ▸ | CMA1 | P23946 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11355224 | 0.94 | SMN1; SMN2 (0.69) | SMN1; SMN2HPGDNPC1RAB9ANAMPT | |
| SCHEMBL26646791 | 0.90 | HPGD (0.73) | SMN1; SMN2HPGDNPC1RAB9ANAMPT | |
| SCHEMBL25970084 | 0.89 | SMN1; SMN2 (0.96) | SMN1; SMN2HPGDNPC1RAB9ANAAA | |
| SCHEMBL12445445 | 0.88 | SMN1; SMN2 (0.81) | SMN1; SMN2HPGDNPC1RAB9ANAMPT | |
| SCHEMBL15978900 | 0.88 | SMN1; SMN2 (0.69) | SMN1; SMN2HPGDNPC1RAB9ANAMPT | |
| SCHEMBL20734830 | 0.87 | SMN1; SMN2 (1.00) | SMN1; SMN2HPGDNPC1RAB9ANAAA | |
| SCHEMBL16361209 | 0.87 | SMN1; SMN2 (0.84) | SMN1; SMN2HPGDNPC1RAB9ANAMPT | |
| SCHEMBL9348556 | 0.85 | SMN1; SMN2 (0.76) | SMN1; SMN2HPGDNPC1RAB9ANAMPT | |
| SCHEMBL30910449 | 0.85 | SMN1; SMN2 (0.87) | SMN1; SMN2HPGDNPC1RAB9ANAAA | |
| SCHEMBL12301884 | 0.85 | NPC1 (0.67) | SMN1; SMN2HPGDNPC1RAB9ANAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1884513-A1 | PYRAZOLE COMPOUND AND THERAPEUTIC AGENT FOR DIABETES COMPRISING THE SAME | Japan Tobacco, Inc. (JP) | 2008-02-06 | — | — | EP | claimed |
| US-20070032529-A1 | Pyrazole compounds and their use as antidiabetes agents | JAPAN TOBACCO INC. (JP) | 2007-02-08 | — | — | US | claimed |
| US-20240092790-A1 | DIHYDROFUROPYRIDINE DERIVATIVES AS RHO- KINASE INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2024-03-21 | — | — | US | disclosed |
| CN-107033069-B | Novel irreversible Bruton's tyrosine kinase inhibitor | 中国科学院合肥物质科学研究院 | 2022-03-04 | — | — | CN | disclosed |
| CN-109053697-A | A kind of pyrimidines and preparation method thereof for anticancer | 张淑华 | 2018-12-21 | — | — | CN | disclosed |
| EP-1965255-B1 | Color filter and method for making the color filter | FUJIFILM CORP (JP) | 2015-08-12 | — | — | EP | disclosed |
| EP-2629149-A2 | Colored curable composition, color filter and manufacturing method thereof | Fujifilm Corporation (JP) | 2013-08-21 | — | — | EP | disclosed |
| US-8137890-B2 | Colored photosensitive composition, color filter, and method for manufacturing color filter | FUJIFILM CORPORATION (JP) | 2012-03-20 | — | — | US | disclosed |
| EP-2028544-B1 | Colored photosensitive composition, color filter, and method for manufacturing color filter | FUJIFILM CORP (JP) | 2011-10-12 | — | — | EP | disclosed |
| US-8029951-B2 | Colored curable composition, color filter and production method thereof | FUJIFILM CORPORATION (JP) | 2011-10-04 | — | — | US | disclosed |
| US-7914956-B2 | Dye-containing negative working curable composition, color filter and production method thereof | FUJIFILM CORPORATION (JP) | 2011-03-29 | — | — | US | disclosed |
| US-20080206660-A1 | COLORED PHOTOSENSITIVE COMPOSITION, COLOR FILTER, AND METHOD FOR MAKING THE COLOR FILTER | FUJIFILM CORPORATION (JP) | 2008-08-28 | — | — | US | disclosed |
| US-20080081268-A1 | COLORED CURABLE COMPOSITION, COLOR FILTER AND PRODUCTION METHOD THEREOF | FUJIFILM CORPORATION (JP) | 2008-04-03 | — | — | US | disclosed |
| EP-1884513-A1 | PYRAZOLE COMPOUND AND THERAPEUTIC AGENT FOR DIABETES COMPRISING THE SAME | Japan Tobacco, Inc. (JP) | 2008-02-06 | — | — | EP | disclosed |
| US-20070212623-A1 | Dye-containing negative working curable composition, color filter and production method thereof | FUJIFILM CORPORATION (JP) | 2007-09-13 | — | — | US | disclosed |
| US-20070190435-A1 | Dye-containing photosensitive composition, color filter using the same, and production method thereof | FUJIFILM CORPORATION (JP) | 2007-08-16 | — | — | US | disclosed |
| US-20070099096-A1 | Dye-containing curable composition, color filter and method of producing thereof | FUJIFILM CORPORATION | 2007-05-03 | — | — | US | disclosed |
| EP-1780598-A1 | COLORED CURABLE COMPOSITIONS, COLOR FILTERS AND PROCESS FOR PRODUCTION THEREOF | FUJIFILM Corporation (JP) | 2007-05-02 | — | — | EP | disclosed |
| US-20070072096-A1 | Negative curable dye-containing composition, color filter, and method of manufacturing the same | FUJI PHOTO FILM CO., LTD. | 2007-03-29 | — | — | US | disclosed |
| US-20070032529-A1 | Pyrazole compounds and their use as antidiabetes agents | JAPAN TOBACCO INC. (JP) | 2007-02-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240092790-A1 | DIHYDROFUROPYRIDINE DERIVATIVES AS RHO- KINASE INHIBITORS | ROCK1, ROCK2, RHOA | SMN1; SMN2 4674/4885HPGD 61/4885NPC1 1946/4885 |
| US-20070032529-A1 | Pyrazole compounds and their use as antidiabetes agents | PYGL, GYS2, AGL | SMN1; SMN2 4705/4885HPGD 3765/4885NPC1 2838/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.