SCHEMBL3933366

SCHEMBL3933366

Fc1c(F)c(F)c(COCc2c(F)c(F)c(F)c(F)c2F)c(F)c1F

nearest known ligand 0.34

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.34
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
CA7 P43166 1/20 0.34
CA9 Q16790 1/20 0.34
MAOA P21397 1/20 0.32
DRD4 P21917 1/20 0.32
DRD3 P35462 1/20 0.32
MMP1 P03956 1/20 0.31
MMP2 P08253 1/20 0.31
MMP9 P14780 1/20 0.31
MMP12 P39900 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12480744 0.87 CA12 (0.32) CA12CA1CA2CA7CA9
SCHEMBL3165171 0.82 CA12 (0.31) CA12CA1CA2CA7CA9
SCHEMBL12445315 0.80
SCHEMBL12445314 0.78
SCHEMBL19795474 0.78 HSD17B10 (0.31)
SCHEMBL12708525 0.76 RECQL (0.33)
SCHEMBL15132093 0.76
SCHEMBL19795489 0.76 PTPN1 (0.33)
SCHEMBL7402746 0.76 MMP1 (0.35) CA12CA1CA2CA7CA9
SCHEMBL15132094 0.74 RECQL (0.32) CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114497689-A Lithium ion battery electrolyte and lithium ion battery 张家港市国泰华荣化工新材料有限公司 2022-05-13 CN claimed
CN-113801019-A Method for preparing poly-fluorobenzyl methyl ether 沈阳中化农药化工研发有限公司 2021-12-17 CN disclosed
CN-107709506-B Surface treating agent containing perfluoro (poly) ether group-containing silane compound 大金工业株式会社 2020-06-16 CN disclosed
US-20120208223-A1 FLUORESCENCE RESONANCE ENERGY TRANSFER ENZYME SUBSTRATES GE HEALTHCARE AS (NO) 2012-08-16 US disclosed
US-20090162838-A1 FLUORESCENCE RESONANCE ENERGY TRANSFER ENZYME SUBSTRATES KUMAR SHIV 2009-06-25 US disclosed
EP-1738171-B1 FLUORESCENCE RESONANCE ENERGY TRANSFER ENZYME SUBSTRATES GE HEALTHCARE AS (NO) 2009-04-08 EP disclosed
EP-1738171-A1 FLUORESCENCE RESONANCE ENERGY TRANSFER ENZYME SUBSTRATES GE Healthcare AS (NO) 2007-01-03 EP disclosed
WO-2005108994-A1 FLUORESCENCE RESONANCE ENERGY TRANSFER ENZYME SUBSTRATES GE HEALTHCARE BIO-SCIENCES CORP. (US) 2005-11-17 WO disclosed
WO-2000048993-A1 ARYLAMINOALKYLAMIDES NOVARTIS AG (CH) 2000-08-24 WO disclosed
US-4990458-A Macroreticular resin used as both adsorber and catalyst MCMASTER UNIVERSITY (CA) 1991-02-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120208223-A1 FLUORESCENCE RESONANCE ENERGY TRANSFER ENZYME SUBSTRATES DLD, DPYD, RNASE1 CA12 1905/4885CA1 1451/4885CA2 2190/4885
US-20090162838-A1 FLUORESCENCE RESONANCE ENERGY TRANSFER ENZYME SUBSTRATES DLD, DPYD, RNASE1 CA12 1905/4885CA1 1451/4885CA2 2190/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.