Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | MME | P08473 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3936735 | 0.75 | EPHX1 (0.38) | CYP2C19ALDH1A1 | |
| SCHEMBL4555890 | 0.74 | CTSK (0.46) | — | |
| SCHEMBL10521828 | 0.73 | FFAR3 (0.35) | — | |
| SCHEMBL3140773 | 0.71 | — | — | |
| SCHEMBL3989590 | 0.70 | EPHX1 (0.37) | CYP2C19ALDH1A1 | |
| SCHEMBL4553549 | 0.69 | FFAR3 (0.35) | — | |
| SCHEMBL164042 | 0.69 | FFAR3 (0.35) | — | |
| SCHEMBL20168856 | 0.69 | FFAR3 (0.35) | — | |
| SCHEMBL3809509 | 0.68 | FFAR3 (0.38) | CYP2C19MMEALDH1A1 | |
| SCHEMBL4581131 | 0.68 | FFAR3 (0.38) | CYP2C19ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2046793-A2 | FUSED PYRIMIDO COMPOUNDS | AstraZeneca AB (SE) | 2009-04-15 | — | — | EP | disclosed |
| WO-2008003958-A2 | FUSED PYRIMIDO COMPOUNDS | ASTRAZENECA AB (SE) | 2008-01-10 | — | — | WO | disclosed |