Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR5 | P35346 | 5/20 | 0.47 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | UTS2R | Q9UKP6 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.45 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.44 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.44 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3537704 | 1.00 | SSTR5 (0.47) | SSTR5HTR4ALDH1A1TP53UTS2R | |
| SCHEMBL4049573 | 0.93 | SSTR4 (0.51) | SSTR5ALDH1A1TP53HPGDRAB9A | |
| SCHEMBL13846090 | 0.87 | HTR4 (0.54) | HTR4 | |
| SCHEMBL3544670 | 0.87 | HTR4 (0.54) | HTR4 | |
| SCHEMBL13175736 | 0.87 | HTR4 (0.54) | HTR4 | |
| SCHEMBL13575476 | 0.85 | SSTR5 (0.55) | SSTR5HTR4ALDH1A1TP53HPGD | |
| SCHEMBL28079636 | 0.85 | HPGD (0.62) | SSTR5ALDH1A1TP53HPGDRAB9A | |
| SCHEMBL13175554 | 0.83 | HRH3 (0.55) | SSTR5ALDH1A1TP53HPGDRAB9A | |
| SCHEMBL17034326 | 0.83 | HTR4 (0.51) | HTR4SLC6A5 | |
| SCHEMBL13845987 | 0.82 | HTR4 (0.53) | HTR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2046793-A2 | FUSED PYRIMIDO COMPOUNDS | AstraZeneca AB (SE) | 2009-04-15 | — | — | EP | disclosed |
| WO-2008003958-A2 | FUSED PYRIMIDO COMPOUNDS | ASTRAZENECA AB (SE) | 2008-01-10 | — | — | WO | disclosed |