Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 4/20 | 0.47 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.47 |
| ▸ | AR | P10275 | 2/20 | 0.47 |
| ▸ | ELANE | P08246 | 2/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 7/20 | 0.46 |
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | USP2 | O75604 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 3/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL145996 | 0.87 | SMN1; SMN2 (0.51) | PGRNR3C1ARELANECYP19A1 | |
| SCHEMBL2030045 | 0.78 | CYP19A1 (0.75) | CYP19A1MEN1MAPTKMT2AKDM4E | |
| SCHEMBL407381 | 0.77 | MAOB (0.50) | PGRNR3C1ARMEN1KMT2A | |
| Thiourea SCHEMBL6715523 | 0.77 | SMN1; SMN2 (0.46) | PGRNR3C1ARMEN1MAPT | |
| SCHEMBL31383405 | 0.77 | GLA (0.60) | CYP19A1MEN1MAPTKMT2AKDM4E | |
| Iodoacetamide SCHEMBL2218893 | 0.76 | SMN1; SMN2 (0.48) | MEN1MAPTKMT2AKDM4EALDH1A1 | |
| SCHEMBL13869332 | 0.74 | CYP19A1 (0.70) | CYP19A1MEN1MAPTKMT2AKDM4E | |
| SCHEMBL28180663 | 0.73 | MEN1 (0.44) | PGRNR3C1ARCYP19A1MEN1 | |
| SCHEMBL17083899 | 0.73 | HSD17B3 (0.56) | ELANEMAPTKDM4EALDH1A1HPGD | |
| SCHEMBL13869439 | 0.73 | CYP19A1 (0.68) | CYP19A1MEN1MAPTKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2044638-A2 | CATHODE COATING | Merck Patent GmbH (DE) | 2009-04-08 | — | — | EP | disclosed |
| WO-2008012581-A2 | CATHODE COATING | MERCK PATENT GMBH (DE) | 2008-01-31 | — | — | WO | disclosed |