Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | TYR | P14679 | 1/20 | 0.44 |
| ▸ | DAO | P14920 | 1/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 7/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | NT5E | P21589 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL145996 | 0.89 | SMN1; SMN2 (0.51) | SMN1; SMN2NPC1RAB9ALMNAHPGD | |
| Iodoacetamide SCHEMBL2218893 | 0.86 | SMN1; SMN2 (0.48) | SMN1; SMN2NPC1RAB9ALMNAHPGD | |
| SCHEMBL407381 | 0.82 | MAOB (0.50) | SMN1; SMN2NPC1RAB9ALMNAHPGD | |
| SCHEMBL3933571 | 0.77 | PGR (0.47) | SMN1; SMN2NPC1RAB9ALMNAHPGD | |
| SCHEMBL30241252 | 0.75 | MAOB (0.54) | SMN1; SMN2NPC1RAB9ALMNAHPGD | |
| SCHEMBL28996736 | 0.75 | MAOB (0.54) | SMN1; SMN2NPC1RAB9ALMNAHPGD | |
| SCHEMBL27715978 | 0.75 | SMN1; SMN2 (0.41) | SMN1; SMN2NPC1RAB9ALMNAHPGD | |
| SCHEMBL259563 | 0.72 | HPGD (0.55) | SMN1; SMN2NPC1RAB9ALMNAHPGD | |
| SCHEMBL28180663 | 0.72 | MEN1 (0.44) | SMN1; SMN2NPC1RAB9ALMNAHPGD | |
| SCHEMBL2030045 | 0.72 | CYP19A1 (0.75) | SMN1; SMN2NPC1RAB9ALMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040072369-A1 | Methods for assaying for urea and kits for use therein | UNIVERSITY OF MARYLAND, BALTIMORE | 2004-04-15 | — | — | US | disclosed |