Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 8/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | NT5E | P21589 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA3 | P07451 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL145996 | 0.88 | SMN1; SMN2 (0.51) | SMN1; SMN2NPC1RAB9ALMNAALDH1A1 | |
| Thiourea SCHEMBL6715523 | 0.86 | SMN1; SMN2 (0.46) | SMN1; SMN2NPC1RAB9ALMNAALDH1A1 | |
| SCHEMBL407381 | 0.81 | MAOB (0.50) | SMN1; SMN2NPC1RAB9ALMNAALDH1A1 | |
| SCHEMBL3933571 | 0.76 | PGR (0.47) | SMN1; SMN2NPC1RAB9ALMNAALDH1A1 | |
| SCHEMBL30241252 | 0.74 | MAOB (0.54) | SMN1; SMN2NPC1RAB9ALMNAALDH1A1 | |
| SCHEMBL28996736 | 0.74 | MAOB (0.54) | SMN1; SMN2NPC1RAB9ALMNAALDH1A1 | |
| SCHEMBL27715978 | 0.74 | SMN1; SMN2 (0.41) | SMN1; SMN2NPC1RAB9ALMNAALDH1A1 | |
| SCHEMBL11425515 | 0.71 | SMN1; SMN2 (0.56) | SMN1; SMN2NPC1RAB9ALMNAALDH1A1 | |
| SCHEMBL259563 | 0.71 | HPGD (0.55) | SMN1; SMN2NPC1RAB9ALMNAALDH1A1 | |
| SCHEMBL28180663 | 0.71 | MEN1 (0.44) | SMN1; SMN2NPC1RAB9ALMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9120850-B2 | Biosensor for detection and visualisation of single-stranded DNA | MEDICAL RESEARCH COUNCIL (GB) | 2015-09-01 | — | — | US | disclosed |
| EP-2170937-B1 | LABELED SINGLE-STRAND DNA-BINDING PROTEIN AND ITS USE IN A BIOSENSOR FOR DETECTION AND VISUALISATION OF SINGLE-STRANDED DNA | MEDICAL RES COUNCIL (GB) | 2014-04-30 | — | — | EP | disclosed |
| US-20110177501-A1 | BIOSENSOR FOR DETECTION AND VISUALISATION OF SINGLE-STRANDED DNA | MEDICAL RESEARCH COUNCIL | 2011-07-21 | — | — | US | disclosed |
| EP-2170937-A1 | LABELED SINGLE-STRAND DNA-BINDING PROTEIN AND ITS USE IN A BIOSENSOR FOR DETECTION AND VISUALISATION OF SINGLE-STRANDED DNA | Medical Research Council (GB) | 2010-04-07 | — | — | EP | disclosed |
| WO-2008152379-A1 | LABELED SINGLE-STRAND DNA-BINDING PROTEIN AND ITS USE IN A BIOSENSOR FOR DETECTION AND VISUALISATION OF SINGLE-STRANDED DNA | MEDICAL RESEARCH COUNCIL (GB) | 2008-12-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110177501-A1 | BIOSENSOR FOR DETECTION AND VISUALISATION OF SINGLE-STRANDED DNA | SSBP1, SSB, DDB1 | SMN1; SMN2 1593/4885NPC1 4651/4885RAB9A 3233/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.