Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 11/20 | 0.88 |
| ▸ | ABCG2 | Q9UNQ0 | 8/20 | 0.50 |
| ▸ | ABCB1 | P08183 | 7/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3937615 | 0.94 | FAAH (1.00) | FAAHABCG2ABCB1CYP1A2CYP2C8 | |
| SCHEMBL3941332 | 0.93 | FAAH (0.88) | FAAHABCG2ABCB1CYP1A2CYP2C8 | |
| SCHEMBL4013784 | 0.92 | FAAH (1.00) | FAAHABCG2ABCB1CYP1A2CYP2C8 | |
| SCHEMBL3933100 | 0.90 | FAAH (0.82) | FAAHABCG2ABCB1CYP1A2CYP2C8 | |
| SCHEMBL4025694 | 0.87 | FAAH (0.78) | FAAHABCG2ABCB1CYP1A2CYP2C8 | |
| SCHEMBL4012669 | 0.86 | FAAH (0.79) | FAAHABCG2ABCB1 | |
| SCHEMBL4017533 | 0.86 | FAAH (0.75) | FAAHABCG2ABCB1 | |
| SCHEMBL4012753 | 0.86 | FAAH (0.75) | FAAHABCG2ABCB1CYP1A2CYP2C8 | |
| SCHEMBL3935486 | 0.85 | FAAH (0.77) | FAAHABCG2ABCB1 | |
| SCHEMBL4017519 | 0.84 | FAAH (0.76) | FAAHABCG2ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009011904-A1 | COMPOUNDS USEFUL AS FAAH MODULATORS AND USES THEREOF | RENOVIS, INC. (US) | 2009-01-22 | — | — | WO | disclosed |