Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 11/20 | 0.77 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.42 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.42 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 2/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | INSR | P06213 | 1/20 | 0.39 |
| ▸ | IGF1R | P08069 | 1/20 | 0.39 |
| ▸ | MET | P08581 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | TEK | Q02763 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3941332 | 0.88 | FAAH (0.88) | FAAHABCB1ABCG2GRM2 | |
| SCHEMBL3937615 | 0.87 | FAAH (1.00) | FAAHABCB1ABCG2HTR6HTR7 | |
| SCHEMBL4012669 | 0.85 | FAAH (0.79) | FAAHABCB1ABCG2HTR6HTR7 | |
| SCHEMBL3933591 | 0.85 | FAAH (0.88) | FAAHABCB1ABCG2 | |
| SCHEMBL4013784 | 0.84 | FAAH (1.00) | FAAHABCB1ABCG2 | |
| SCHEMBL3933100 | 0.83 | FAAH (0.82) | FAAHABCB1ABCG2IGF1R | |
| SCHEMBL4017519 | 0.83 | FAAH (0.76) | FAAHABCB1ABCG2HTR6HTR7 | |
| SCHEMBL3933423 | 0.83 | FAAH (0.87) | FAAH | |
| SCHEMBL3941505 | 0.82 | FAAH (0.80) | FAAHABCB1ABCG2TRPV1 | |
| SCHEMBL4012448 | 0.82 | FAAH (0.57) | FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009011904-A1 | COMPOUNDS USEFUL AS FAAH MODULATORS AND USES THEREOF | RENOVIS, INC. (US) | 2009-01-22 | — | — | WO | disclosed |