Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 11/20 | 0.76 |
| ▸ | HTR6 | P50406 | 3/20 | 0.46 |
| ▸ | HTR7 | P34969 | 2/20 | 0.46 |
| ▸ | IGF1R | P08069 | 2/20 | 0.43 |
| ▸ | CDK2 | P24941 | 2/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | INSR | P06213 | 1/20 | 0.43 |
| ▸ | MET | P08581 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | TEK | Q02763 | 1/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.40 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.40 |
| ▸ | TNF | P01375 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4012669 | 0.94 | FAAH (0.79) | FAAHHTR6HTR7IGF1RCDK2 | |
| SCHEMBL3937615 | 0.86 | FAAH (1.00) | FAAHHTR6HTR7ABCB1ABCG2 | |
| SCHEMBL4013784 | 0.85 | FAAH (1.00) | FAAHABCB1ABCG2 | |
| SCHEMBL4019416 | 0.85 | FAAH (0.70) | FAAHHTR6HTR7IGF1RCDK2 | |
| SCHEMBL4019421 | 0.85 | FAAH (0.70) | FAAHHTR6HTR7IGF1RCDK2 | |
| SCHEMBL3933752 | 0.84 | FAAH (0.89) | FAAH | |
| SCHEMBL3936220 | 0.84 | FAAH (1.00) | FAAH | |
| SCHEMBL3933591 | 0.84 | FAAH (0.88) | FAAHABCB1ABCG2 | |
| SCHEMBL3929528 | 0.84 | FAAH (0.85) | FAAHHTR6HTR7IGF1RCDK2 | |
| SCHEMBL3941332 | 0.84 | FAAH (0.88) | FAAHABCB1ABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009011904-A1 | COMPOUNDS USEFUL AS FAAH MODULATORS AND USES THEREOF | RENOVIS, INC. (US) | 2009-01-22 | — | — | WO | disclosed |